I have been on LDN for 3 weeks now, I am currently on 3mg, will increase to 4.5mg over the next 2 weeks.
I am in Ireland, my Pharmacist has told me that this is currently an "unlicensed" medication here, and I have had to jump through some hoops to get it.
My Rheumatologist prescribed this for Seronegative Arthritis pain that does not respond to regular Arthritis Treatments. I am 35 and have been suffering with pain in all joints after a 10yr remission, for the last 5 years now. They have no patient information leaflets on this medicine, and directed me to an online resource that is only about Naltrexone for substance abuse, so it is not very helpful to me.
My questions really are:
1.Does LDN have to be taken at night for maximum benefits?
I find the sleep disturbances/vivid dreams are getting worse, more sinister, and I am waking up miserable. I want to get the most out of this drug, but I do not like the sinister dreams!
2.Do I have to stop taking LDN before an anesthetic/sedation for a procedure? And if so, what happens if I ever need an emergency anesthetic?
I am scheduled for a colonoscopy in a weeks time, my Rheumatologist advised that it is not necessary to stop LDN in advance of this, the GI specialist advised I should stop 2 days prior, and I have read online that anesthetic administered while on LDN can lead to instant withdrawal symptoms which can put the body into shock. I am very confused on this.
3.Is it DANGEROUS to take Opiate Painkillers and LDN?
I have tramadol which I really need to take sometimes for severe pain. I currently take LDN at night approx 9pm. Is it SAFE to Take one dose of 100mg Tramadol-instant release- the next day. The latest I would take it would be 3-4 hours before my LDN dose.
As much detail on this would be appreciated, ie. Why is it not safe etc. Are there decent painkiller alternatives? NSAIDS, or paracetemol do not cut it.
4. Alcohol and LDN.
I do not drink very often, but when I do I usually drink to get drunk! ie. more than a bottle of wine. Is this DANGEROUS while on LDN. Should I skip my nightly dose if I am DRUNK going to bed?
I know that drinking in excess is never a fabulous idea, but it is a reality, and any information here would be appreciated, I am scared to touch a drink at the moment.
I am aware that LDN coats opiate receptors all over the body, including the brain, I do not want to mess with these if it is unsafe.
5.Is LDN classed as a painkiller?
A Rheumatologist repeatedly described this treatment as both an opiod antagonist and a Painkiller. From what I have read these descriptions seem to be conflicting.
I have read extensively on how LDN works to promote immune supporting endorphin's and suppress TNF response, this does not sound like a PAINKILLER to me, even though the resulting response is a reduction in pain. Again, I am confused on this, and currently do not trust this young Rheumatologists knowledge of the drug (not the original prescriber)
Thank you very much for reading these questions, I am hopeful that LDN could be a great drug, with little side effects, but these questions really are burning for me, and maybe the lack of concrete information I have received thus far is contributing to my wacky sleep disturbances!!