Hi all, my husband (34yrs, very, very fit and healthy man with the exception of ITP) has had ITP for just over a year and a half. He has tried (in order) prednisolone, Ivig, menthol prednisolone, eltrombopag, romoplostim. None of which has worked. During this time his platelet counts has been as high as 265 and lowest being 2. The most effective drug was romoplostim with an average count of around 165 however eventually his counts went to 5 and stayed there. On 10th may, he had his spleen removed, we done this because nothing else has worked. Since the operation, he has had two blood tests. Day after op (74) and 5 days after op (124). We are now 9 days after op and he thinks his count has crashed because he is showing signs of petechie and blood blisters in his mouth. We will go to hospital on Monday 21st to get checked. The big question is: what now?, what's next?, what if we can't get his counts above 5?