My husband was diagnosed in May. Nothing but NPlate raises hiis count. Rituxan, IVIG, platelet transfusions and prednisone were of no real help. I keep reading everyones comments about their count being 20,000 to 50,000 but his Dr keeps giving injections and wants him about 300,000 because about every 10 days it drops to between 17,000 and 60,000. Last week it was 635,000 and 5 days later 52,000. Very confusing! Do many of you not take a treatment and just live with very low counts? Scares me what NPlate might cause down the road and wonder how long can someone stay on this treatment? Trying to get a balance on how often to get the treatment is so frustrating.