Jacobs Syndrome (XYY) extra chromosome

[StaceD]

Hello, first time posting!

My partner & I have been diagnosed with MFI and genetics testing has recently shown that my partner has any extra Y chromosome (XYY or also known as Jacobs Syndrome)

This has been diagnosed as the reason for our infertility however research shows that Jacobs Syndrome apparently has NO affect on male fertility? I’m so confused! If anyone has any experience or words of advice I would love to hear from you. Thankyou

[andylins]

Well, I've never been in the case myself. But I felt I couldn't read and then just run away. I'm sorry you're facing this trouble. I did some research. It's said, most boys with 47, XYY syndrome go through normal sexual development. And fertility is expected to be normal!! However, some boys with the syndrome may develop testicular failure. (This is the condition when the testes can’t produce sperm or testosterone). This can lead to problems with fertility!!! So probably you have to check this one with your dr.

Then ''Boys with 47, XYY syndrome have one X chromosome and two Y chromosomes in each cell of the body. This typically happens due to a random event. When a sperm that has two Y chromosomes fertilizes an egg, the resulting baby will be a male with two Y chromosomes and one X chromosome. It is also possible that a similar random event could occur very early in an embryo’s development. This can produce a boy who has some cells that have two sex chromosomes and some cells that have an extra Y chromosome.'' - Nothing mentioned about any abnormalties in the embies and babies!

Men who have this syndrome are not thought to be at an increased risk to have a child with chromosome differences. Some sperm cells will have an extra Y chromosome. However, it is thought that these cells are less likely to be able to survive to fertilize an egg!! - I'd have this fact also checked with a dr.

So from what I've got to know there are at least 2 ways this syndrom CAN affect on male fertility!! Do check them out with your dr! Wish you all the best of luck and soon babydust! Hugs x