I was only diagnosed with Hughes syndrome a couple of months ago by a Stroke Consultant and have been on warfarin for about 5 weeks. INR going up but very slowly. One of the things I am excitedly looking forward to is improvement in my memory. I think I have had Hughes for about 20yrs (they found it in my blood in 2000 and didn't tell me) and people have always joked about my patchy memory. At the moment my INR is only 1.4 - at what INR have others noticed their memory getting better? I have always relied on Outlook etc to be my memory but social stuff like remembering emotions attached to events are just lost. They are aiming for an INR of 2.5 which I hope will be enough!