Mounjaro Weight loss Jag

[Lupus1976]

I have lupus and APS and I’m on azathioprine, aspirin, hydroxychloroquine, prednisolone and ramipril.

im wondering if anyone has tried the weight loss injection mounjaro if you are currently taking any of lupus or APS meds? If so, were you ok?

put on loads of weight since taking my meds and got the steroid moon face. So want to try something.

Thanks ,

[lupus-support1 Administrator]

Never ever take anything without the permission and advice of your Consultant!

As someone with SLE & taking corticosteroids for decades, the weight gain (middle of the body) & “moon face” is the result of the steroids.

If you want to lose weight, get help from your GP who can refer you to a specialist dietitian.

As far as I am aware, no injection can magically lose weight. In addition, whatever is in it could cause you major problems. If you are eating healthily, that’s most important.

Exercise: get advice from your local physiotherapist. There may be classes available for you to try. As it’s a physiotherapist, they will understand your needs.

Good luck and be well!

Ros

[Lupus1976 in reply to lupus-support1]

Thanks for your help. Yip I have the definite moon face now and I just can’t seem to control if just now.

Thanks for your help

[lupey01]

Hello! Fellow lupus and APS friend here. Not currently on any traditional lupus meds, been in remission for a few years.

Had years of high dose steroids that caused over 50lbs weight gain.

Currently on warfarin for APS and beta blocker for migraines, in addition to Ubrelvy. I was on Wegovy for 6 months and safely lost 22 lbs. I stalled and hit a plateau and asked pcp to switch to zepbound. Been on it for 5 weeks lost 4lbs. Discuss it with the Dr you set the most and if they need to refer you, take the referral. There are some of us that will never lose the weight our bodies have gained during years of trying 30+ different meds to get our lupus symptoms under control, just by diet and exercise alone. Don't let anyone shame your choice to want to try a glp1. Just be informed and aware.

Best of luck to you!

[Lupus1976 in reply to lupey01]

Thanks for your response. The company have refused me it because of the meds I’m on and conditions. Hopefully there’s another way 😢

[user666]

ozempic and other similar drugs do increase your chances of clotting significantly ( 266% increase) and thus often the risk is greater than their benefit in APS patients who are not obese. If you are obese or have pre diabetes a doctor might sign off on it but otherwise you likely should be cautious of the risks.

pubmed.ncbi.nlm.nih.gov/340...

[Lupus1976 in reply to user666]

Thanks for your help. Just got overweight when taking steroids. Will just diet on own as not worth risk. Thank you

[Pooky7 in reply to user666]

Ozempic is made from lizard venom. It paralyzes the stomach so you feel full and don’t eat. The food rots in your gut. We are not lizards and don’t do well with rotting food. It can cause permanent damage, along with thyroid cancer. So if there is a shot or pill that sounds too good to be true. Be cautious. I do intermittent fasting and no sugar. It has been the best thing for me to loose weight and I sleep great Blessings

[KellyInTexas Administrator in reply to Pooky7]

Really! I had no idea. Thank you for that. That explains the “why” of the paralytic ileus that seems to plague many.

[kiminabmw in reply to Pooky7]

It is actually a synthetic version of a hormone in the venom, not the gila venom itself.

[Pooky7 in reply to kiminabmw]

I learned about the venom by Dr Ardis Where did you hear it was synthetic? I would like to learn more. Thank you 😊

[kiminabmw in reply to Pooky7]

After learning that the venom of a Gila monster lizard contained hormones that can regulate blood sugar, Daniel Drucker started wondering why. And could the venom somehow help treat diabetes?

Drucker is a scientist and endocrinologist at the University of Toronto who has dedicated his career to understanding the universe of hormones in the body, which do everything from regulating appetite to helping with digestion. His curiosity about the Gila monster led to a call with a zoo in Utah. In 1995, Drucker had a lizard shipped from Utah to his lab and began experiments on the deadly venom.

Ten years later, a synthetic version of a hormone in the venom became the first medicine of its kind approved to treat type 2 diabetes. Known as a GLP-1 (for glucagon-like peptide-1) receptor agonist, the medicine set off a cascade of additional venom-inspired discoveries.

*** Pooky7, do a search on "Danial Drucker Toronto Ozempic" and you can read many articles and videos. Only reason I knew it was because my nephew was put on Ozempic several years ago. My nephew became diabetic from high dose-long term use of steroids because of his CAPS diagnosis.

[KellyInTexas Administrator in reply to kiminabmw]

Thank you.

I am highly allergic to glucagon. I found out during an imaging study before a GI scan. It’s used to “paralyse” the bowels for a second for images so photos without movement can be obtained. The surgeon wants no surprises when he goes into surgery.

[kiminabmw in reply to KellyInTexas]

Hi Kelly, I hope you are doing OK. My nephew, CAPS survivor since 2019 is doing well. They finally have him down to just taking Warfarin and Plaquenil, and hopefully he'll continue feeling good. Be Well Kelly.

[Pooky7]

interesting. Thank you