Does any know if APS is related to Hemochromotosis ( absorbing too much iron)

[APSdsntHaveMe]

My brother who has many symptoms of aPS but refuses to get tested was just diagnosed with hemochromotosis. I was just wondering if it could related.

[MaryF Administrator]

Hi There, I have found this for you, which may help with any conclusions you come to: ncbi.nlm.nih.gov/pubmed/182.... Maybe other people will have similar backgrounds to yours and can help further. Mary F x

[SCMW in reply to MaryF]

Hi MaryF, can you tell me the summary of the above link as I can’t access it? Is there a link between haemachromatosis and aps? My mother is being tested following repeated abnormal clotting tests & I have Behcets. Thanks.

[MaryF Administrator in reply to SCMW]

It is not uncommon to have a Thyroid problem with Hughes Syndrome/APS. I have copied and pasted the contents of the paper for you in case it is of interest:

Minerva Med. 2007 Dec;98(6):769-72.

A possible link between genetic hemochromatosis and autoimmune thyroiditis.

Tamagno G1, De Carlo E, Murialdo G, Scandellari C.

Author information

1

Department of Medical and Surgical Sciences, Internal Medicine III, University of Padua, Padua, Italy.

Abstract

The systemic involvement that often characterizes genetic hemochromatosis is well known. Although evidence of iron storage in endocrine glands has been reported, the possible functional changes due to altered thyroid in course of hemochromatosis have been not clearly defined so far. Thyroid may be directly affected by iron storage in the gland as well as functionally altered due to iron accumulation occurring in the pituitary. The prevalence and the pathogenetic mechanisms of primary thyroid illness in patients with genetic hemochromatosis are still largely unknown. Hereby, we describe two patients affected by genetic hemochromatosis who developed Hashimoto's thyroiditis. Taking into consideration the possible links occurring among iron overload, thyroid gland damage and thyroid dysfunction, we hypothesize that hemochromatosis could have been an enhancing factor for the development of primary thyroid disease in these patients. Potentially, this process might also determine new onset anti-thyroid autoimmunity or overlap it. We conclude that systematic studies in large and heterogeneous populations will be necessary in order to assess the risk of development of primary thyroid disorders in course of genetic hemochromatosis and, more generally, chronic iron overload conditions. In our mind, thyroid function should be periodically checked in all patients with chronic iron overload conditions.

PMID: 18299688

[Indexed for MEDLINE]

MaryF

[daisyd]

Hi i have had a blood test DAT, it tells what level of iron you have in your body, mine was half of what it should be.

They have checked me by colonoscopy and Gastroscopy no bleeding. My Husband eats the same food as me so ? Not caused by diet.

My full blood count was normal ? What would have happened if I hadn't had this blood test? I am now on iron medication .

DAT test requested by st Thomas's

[swirl]

I am the contrary. Tests show that I don´t have enough iron in my body (less than the half) but my full blood count is normal. I´m taking iron tablets now because my Doc. says that if this situation continues, my number of hematies could decrease.

[daisyd in reply to swirl]

Hi swirl, what is Hematies, thanks

[swirl in reply to daisyd]

Sorry!!! jajaja I wrote it in spanish. It Is erythrocytes