Sticky Blood-Hughes Syndrome Support
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Lupus Anticoagulant

Hi again everyone, I just wanted to thank people for their lovely responses to my last two questions. I have another! (And many more) I'm still waiting for appointment with a haemotologist despite my daily attempts to chase it up. Thankfully I'm under a consultant obstetrician who is on the ball so I'm getting the right treatment now I'm pregnant again. I tested positive for lupus antibody twice but now anti cardiolipin antibodies. What does this mean? Are they the same? Do they have the same effect or is one worse?

3 Replies

Sorry I meant to say NOT cardiolipin antibodies. That was negative.


There are three tests for Hughes - Lupus Anticoagulant (LA), Anti Cardiolipin Antibodies (aCL) and anti - Beta2 glycoprotein1 (anti B2GP1). You do not have to be positive to all three. So it sounds like you are positive to the LA but not to the aCL. Thats fine, some people are the other way around some people like me just get positive to anti B2GP1. Some dont get positive to any of them and are known as seronegative and diagnosed on clinical history.

Have a look here on the HSF website as it explains about the blood tests.


Yes to everything written in reply above, and best of luck with your pregnancy and glad your obstetric care appears to be on the ball! Nary F x


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