Preservatives are increasingly recognised as having a negative impact on ocular structures even in concentrations as low as 0.005%¹. Patients with Dry Eye Disease (DED), particularly those who require frequent use of lubricants or other topical therapies, should avoid ocular lubricants that contain Benzalkonium chloride (BAK)².
Please read the link
thea-pharmaceuticals.co.uk/...
I use monoprost that is preservative free in the uk it is called lantaprost
However, they gave me alphagan and two other kind of drops in the last 3 months azarga being one of them, that was hell...
They had preservatives in them and in france they did not give me another choice. fortunately I have been able to stop taking them due to having SLT. The worry of what it could do to my eyes gave me severe anxiety....
I tried to get alphagan p (purite) that is preservative free. I even wrote to the manufacturer allergan in france and india to buy them myself... I did not even get a reply from france.... just incase I have to go back on that drug... I am still struggling to get it here I have to get my opthalmogist to complete a special form to the government... it must be pricey I don't know.
The reason for telling you all this is I do know what drops you are all taking, if they have preservatives. If so try and get an alternative to what you are taking. They are simply harmful to your eyes if they have preservatives and dry out your eyes. And that goes for dry eye drops for dry eye, choose preservative free. I use Thea preservative free eye drops for dry eyes.
Here is an excellent link for the uk with all the eye drops for glaucoma
specsavers.co.uk/eye-health...
below i have cut and pasted the list of eye drops. i have gone through the whole list and checked which ones have preservatives... i have written beside each eye drop....
Prostaglandins
The medication used in this category of eye drops work by improving drainage of fluid from the eye to specifically to reduce high eye pressure (ocular hypertension).
Some primary examples of these include:
Latanoprost (Xalatan) (PRESERVATIVE FREE)
Bimatoprost (Lumigan) YOU CAN GET PRESERVATIVE FREE
Travaprost (Travatan) TRAVPOST Z YOU CAN GET PRESERVATIVE FREE
Tafluprost (Zioptan) TRAVOPOST HEALIO IS PRESERVATIVE FREE
Latanoprostene Bunod (Vyzulta) PRESERVATIVES
Some of these medications may cause certain changes to the eye, such as slight redness of the eye, changes to the iris colour, and darkening and/or lengthening of the eyelashes.1 These eye drops should be used once a day, usually at night.
Prostaglandins are generally considered to be effective in managing open-angle glaucoma (the most common form of glaucoma).2
Beta-blockers
This class of glaucoma eye drops works by reducing the production of fluid in the eye, and a commonly used medication that does this is Timolol (Timoptic).
Other examples of beta blockers include:
Levobunolol (Betagan) YOU CAN GET SINGLE DOSE PRESERVATIVE FREE
Carteolol (Ocupress) PRESERVATIVE IN THIS
Betaxolol (Betoptic) PRESERVATIVE IN THIS
Metipranolol (OptiPranolol) PRESERVATIVE IN THIS
It is worth noting that beta blockers can cause some systemic (whole body) side effects such as slow pulse, asthma, dizziness, and fatigue.1 Your ophthalmologist can help you with some techniques to minimise these risks2.
These eye drops are generally used once or twice a day. They can also be prescribed in combination with other types of medication for best results.
Alpha-adrenergic agonists
Alpha agonists are a class of glaucoma eye drops that both decrease fluid production and increase fluid outflow. Examples of these include:
Brimonidine (Alphagan-P) PRESERVATIVE IN THIS. YOU CAN GET ALPHAGAN PURITE PRESERVATIVE FREE
Iopidine (apraclonidine) YOU CAN GET PRESERVATIVE FREE IN THIS ONE
Generally, allergic reactions are the most common side effects of glaucoma eye drops. This can be due to a common type of preservative used in the production of certain eye drops.
However, the preservative used in Alphagan-P actually breaks down into natural tear components, and is, therefore, better tolerated by people who are allergic to glaucoma eye drops (either the preservative in the drug or the drug itself).2 This type of glaucoma eye drop usually needs to be put in the eyes 2-3 times a day.
Carbonic anhydrase inhibitors
This group of glaucoma eye drops works by reducing the amount of fluid that is produced in the eye. Examples include:
Dorzolamide (Trusopt) PRESERVATIVE FREE
Brinzolamide (Azopt) PRESERVATIVE IN THIS
Carbonic anhydrase inhibitors are also available in pill form. Some people find that they have some problematic side effects when taking these, but your doctor will talk them through with you.
Carbonic anhydrase inhibitors are typically used 2-3 times a day, sometimes alone, but usually in combination with another anti-glaucoma eye drop.
Combination eye drops
Some people need more than one type of medication in order to control their intraocular pressure, which is where combination eye drops can help. They also reduce exposure to preservatives and potential allergic reactions.2 If you are prescribed a combination eye drop, your ophthalmologist will go into detail as to why and how they fit into your treatment plan.
Common combinations include:
Cosopt – a combination of timolol (beta blocker) and dorzolamide (carbonic anhydrase inhibitor). Cosopt PF is the preservative-free version. The drug is also available in generic form COSPOST PF IS THE PRESERVATIVE FREE VERSION
Combigan – a combination of brimonidine (alpha agonist) and timolol (beta blocker)
PRESERVATIVE IN THIS
Xalacom – a combination of latanoprost (prostaglandin) and timolol (beta blocker)
PRESERVATIVE IN THIS ONE
Simbrinza – a combination of brinzolamide (carbonic anhydrase inhibitor) and brimonidine (alpha agonist). This combination is free of beta blocker and may be suitable for people who cannot take beta blockers.
PRESERVATIVE IN THIS ONE...
this sounds interesting...
A new class of anti-glaucoma medication called Rho Kinase (ROCK) inhibitors has passed clinical trials in the UK, and this group of medications works by increasing the drainage of fluid from the eye.2
This new medication is the first of its kind in over 20 years and represents a huge leap forward in the science behind how certain drugs can manage glaucoma symptoms. To find out more, talk to your ophthalmologist.
Hope this helps. valfrance