I have been on duloxetine for nearly a year now. Currently I am on 60mg. I had the usual side effects at the beginning like nausea and feeling a bit odd in general. I really wanted this drug to work for me as I tried so many other antidepressants before and had to stop. So i was persistent and kept up with it. It worked wonders on my joint pain but made me feel more zombified in my head. Currently I am experiencing really horrible restlessness in my whole body. Have not slept for two weeks now more than 2 h a night. Feel shaky and my jaw trembles. I am really considering coming off them fully. Seeing gp tomorrow. Has anyone experienced similar problems?