Please guide, PCOS and struggling to conceive

[Hussain_]

Hi. I have been diagnosed with PCOS and had just finished second letrozole cycle. I was prescribed to take 5 mg but got 3 follicles therefore doctor told me to not to try for a baby that month. My dose was reduced to 2.5 mg, to avoid hyperstimulation due to PCOS but on this lower dose I had 10 mm follicle on 13th day ultrasound scan. Then doctor advised me for second scan on day 20, which showed 18 mm follicle. I got ovulation on day 23 of the cycle and got periods on 40th day. Ovulation test showed a higher progesterone level (60 nmol/l).I need suggestions for the following things.

(1) Now for this month what dose I should take as neither 5 mg nor 2.5 mg is appropriate for me?

(2) From my first two letrozole cycles I found that I have longer luteal phase (17-20 days). How we can improve it? Can longer luteal phase be a problem to conceive?

(3) Does high progesterone creat problems? How I can lower it as well. I am also taking inofolic alpha. Can it be a cause of low estrogen/ high progesterone or longer luteal phase?

[Icequeen11]

As a PCOS girlie, I had the same happen to me with two IUIs last year. My previous clinic couldn’t quite figure out the medication so I moved to a different clinic and we decided that IVF was best for me. I was advised to start taking myo-inositol (a supplement for healthy ovarian function and hormonal balance) and this revolutionized my cycle. Over three months it shortened from 35/36 days to about 30/31 and it also helped manage other PCOS symptoms. Ask your doctor about it!

[Hussain_ in reply to Icequeen11]

Oh thank you very much for reply.

[Eloquentia]

Hi! PCOS here too, we got pregnant with IVF. Never did IUI, we were told IVF was our best chance to went straight for that and don't regret it. Like Icequeen11, I too took myoinositol to help regulate periods and also eliminated sugar from my diet. Both helped, I think. Very best of luck on your journey!

[Hussain_ in reply to Eloquentia]

Thank you very much 👍 I am happy to hear that IVF worked for you.