Another BFN💔 this is our third negative transfer now so something isn't right 😭
Booking to have an ERA and NK cells test. Has anyone done these tests and got the answers you need?
Currently have no more embryos left. My wife will be going through egg collection again in the next 2 months. She is 30, we have thought about PGS testing but the package with our clinic is a lot more. Is PGS testing worth it for someone of her age ?
Feeling heartbroken 💔
I'm so sorry to hear this. We opted not to do PGS testing on our embryos due to age and went for the ERA instead which has worked out for us. I needed a full 24hrs of progesterone more than "normal" ladies. Good luck and meantime hugs.xx
What are Era and pgs tests?x
Pgs testing is the check for euploid embryos (the correct number of chromosomes) in he blastocyst, they take a biopsy for this. ERA (endometrial receptivity array) testing is where they take a biopsy of the womb to check when your lining is receptive to an embryo for implantation. Hope that helps.xx
Thank you. Sometimes it’s easier to ask on here than google 🥲
You're welcome!!xx
That makes sense. My wife has just turned 30, ERA and NK cells testing hopefully should give us some answers. I'll let you know how I get off x
Best of luck!!xxx
So sorry to hear this, I am just about to start the process for an ERA test, hope we both get some answers. Hope you can have a relaxing weekend with lots of treats xx
Please let me know how you get off with yours. Hopefully I can start my ERA test with my next period 🙏Thank you. I'm having a chilled weekend and just being thankful for the other things I have in life.. trying to think positive ❤️ x
I'm so sorry to hear this Hope 😢
I had PGS testing but I'm 41. Maybe explore the ERA and NK cells first?
Sending love to you both xx
I’m really sorry to hear this Hope. My clinic told me that I was 32 they wouldn’t really recommend PgS - perhaps explore ERA/Alice/EMMA first? Hope you are able to take it easy on yourselves this weekend xx
Yeah we plan to do just the ERA and NK for now. Thank you .. it's been a tough day but have to keep positive xx
Hi hope. I’m so sorry to hear this. I had 6 failed transfers before getting pregnant. We hadn’t done the PGS testing. Though if our 7th transfer hadn’t worked it probably would of been our next step.
We did both ERA and nk cell testing. I had high nk cells so I took intralipids on the run up to transfer and after transfer. The era test I found was the best thing we did as I was a day 6 transfer not a day 5. I found out I needed exactly 134hrs of progesterone. Also make sure your getting enough progesterone I realised on previous rounds I wasn’t getting enough on the round we got pregnant I was on 700 mg of progesterone.
And the final thing my clinic did which I never heard of before was they gave me an infusion of a drug called atosiban right before transfer, I do believe this worked.... what it does is stops the uterus from contracting after transfer so it prevents your uterus from rejecting the embryo. Hope some of this helps. Please don’t give up you will get there. It wasn’t an easy journey for us either and I thought we would never get there but after 6 egg collections and 7 transfers we are now 26wks pregnant. Ita like putting a jigsaw puzzle together 💖 good luck xx
Ahhh wow seems you had a tough journey.Your message is giving me hope, thanks for sharing that 🙂 I'm glad you got the answers from those tests
We have decided to do NK Cells test / ERA.
I did have my progesterone levels checked before transfer and they were low. They increased by adding X1 lubion injection (I was already taking 3 cyclogest a day, I think that's around 625mg per day), I'll have to double check with my clinic.
My wife is going to have her egg collection next month (I'm then planning on carrying her eggs) she has been preparing herself incase this transfer failed, by taking C0Q10 vitamins and a few others. Plus cutting out any alcohol and caffine. Fingers crossed we will have a better bunch of embryos next time around 🙏
If you have any tips on ways to improve egg quality or advice, would be really helpful 🙂
I'll ask my clinic about astiban..🙂
Thank you so much for your advice. I really appreciate it x
Sending big hugs 💕. This journey is so cruel.
My wife and I have just had our second failed transfer and we are going to look into ERA, NK testing and anti coagulation blood tests too. I was also talking to my acupuncturist who recommended Alison Savory who specialises in Chinese herbs for fertility. She suggested my womb lining might be too thick by the time of transfer so maybe I wasn’t getting good blood flow in the uterus for implantation too.
Good luck for your next cycle 🤞🏻. Inbox is always open if you need a chat xx
Sorry to hear about your failed transfer. It's heartbreaking each time 💔
Good luck with your tests. I hope you get the answers you need. Let me know how you get on with them 🙂
I'm going to book in to start my tests hopefully with this period. I feel it's been a long journey but fingers crossed these tests will give me some answers 🤞
Thank you, same to you xx
So sorry to hear 😢 I’v really struggled with our negative this time. Dark thoughts about what if this never happens. I feel like someone has died 💔
Can I ask, what is PGS?
There’s lots of PGS info on hfea.gov.uk/treatments/expl...
Totally understand, it’s so hard not to get overwhelmed. We’ve really tried to take it one day at a time this week, thinking or planning ahead was just making things worse.
Take care of yourselves 💕xx
So sorry about your negative test. It’s heartbreaking 💔
I had 3 BFNs before doing an ERA test which showed that I need an extra day of progesterone before transfer. So like @teenytiny we will do our next transfer on day 6. Hoping this is our answer!! Xx
So sorry to hear this. Our embryos are all PGS tested and I have had an ERA and my NK cells tested. We made a lot of changes to our last transfer as a result which currently has been successful. I’m 42 now so I can’t say for sure if I would have done PGS testing at 30 (and wasn’t doing IVF AT 30). Perhaps start with the ERA and NK cells in the first instance if you can? Xx
Hi my wife is 31 and we ar won our 3rd fet. She had a miscarriage on the first and a failed cycle on the second. For this cycle we’re on now we did the nk cells test which came slightly elevated but nothing crazy. Regardless we decided to do the intralipids treatment after one of the nurses in the clinic recommended it strongly. We got a positive pregnancy test yesterday but with a slightly low hcg level of 67 so we need to repeat it on Monday to confirm.
We asked several doctors about the NKcells and the ERA. We spoke to 3 doctors. They all agreed that the intralipids had some evidence of helping women who had had miscarriages or failed cycles. With regards to the ERA the attitude from all of the, was like “eh you would do it and it would be good information to have but I don’t think it’s the make or or break it factor”. Nevertheless, if your wife has an uncommon transfer window the ERA can identify that if it’s significant. Good luck.
Hi, I’m so sorry, it’s really difficult to go through IVF and get a BFN...
We have done PGS testing and we are 17 weeks pregnant now, this was our second PGS tested transfer, the first one ended with Chemical pregnancy...
I’m 36 and had a few miscarriages before this pregnancy. PGS testing was something that clinic offer to us to increase our chance. I’m really happy we went that route. We haven’t done ERA and seems like we didn’t need it...
Best of luck.
I’m sorry about your BFN. I also received had my 3rd failed cycle this week and have decided (after a double transfer of my last two frosties this month, both very low grades) to do the ERA test and PG testing (I’m 34) should I have another failure... I feel I need to get all boxes ticked! So I don’t have experience with this or a positive story get but in the same mindset as you test wise!
I’m so sorry, it never gets any easier seeing a negative test result 💔
I hope your doctor can find you some answers to improve your chances when you start again. Best of luck 🤍💫
I had a failed cycle and couldn't understand why so we opted to do the ERA test and I needed a full day less of progesterone. We are now 8 weeks pregnant with a PGS tested embryo. I am soo soo glad we did the ERA as it told my doctor exactly what my body needed to implant
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