NK cells results - can anyone help?

Hi ladies,

I have just had my Natural Killer (NK) cell test (bloods and biopsy) results back.

The results were mixed.

However, I have high/abnormal "TH1/TH2 intracellular Cytokine ratios" - my TNF is 42% and IFN is 25%.

Has anyone else had these tests and results? Just wondering if 42% for TNF is very high in the IVF world?

Thanks, Beatrice xx

[Zebedee1971]

What did your consultant/specialist say? I'm with an immunology/miscarriage specialist and he told me exactly what my results were and what they should be in a normal range, and what drugs he'd prescribe to treat it.. However, I know that lots of ivf clinics do the tests now... but they're not necessarily experts in the field. Who are you with? There are 3 specialists that are the best to consult with, as they really know their stuff : doctor hassan Shehata at crp clinic, doctor quenby at Warwick and doctor gorgy in London. X

[Hidden in reply to Zebedee1971]

My doctor is on leave until the end of January! Leaving me wondering what on earth my results mean. I am with CRGH.

Thanks so much for the contact details. Out of the three specialists who would you recommend?

Can I ask what your results were? I have no benchmark and just really confused x

[Zebedee1971 in reply to Hidden]

Not sure if any of this is helpful but I have my results from Doctor Shehata.

The normal ranges are:

Tnf alpha (il 4) 19-57.6

Ifn gamma (il 4) 8.8-21

Tnf alpha (il 10) 13.2- 31

Ifn gamma (il 10) 6.1-14.8

I don't know if these are percentages or some other form of measurement. But they are the ranges on my results. I have a high Tnf alpha (il 10) @38.8, so just out of normal range x

[SCHNOW]

Hi, how is your treatment now? I just received mine today with TNF (il 10) 57.6 and IFN (il 10) 40.2. Looks really high! I am at CRGH as well.

[N-A-58]

..

[Blythsford]

Would you recommend bloods or biopsy? Which gave you more helpful results? What was your treatment?

[Icsi_Wincy_Spider]

Hi Hidden, not sure if this is similar but my blood test came back as ANA Positive which is similar (where out immune system attacks itself / any foreign objects) and until I discovered this, I had 3 failed transfers. This time though, with 3 intra lipid sessions (2 hours each) I got my BFP. Hope this helps and good luck xxxx 😘😘