So we’re still on this big rollercoaster 🎢 yesterday there was more bleeding and red but it’s not heavy, doesnt even show on a pad! By last night it was really light pink!! So I thought it was going......but no got up this morning and the red is back but still not heavy!!
Really don’t no what to think Now but guess we’ll find out tomorrow xxx
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Lisaworthy1981
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Good luck! Also 10dp5dt, but scared to test as I’ve been so sick throughout the 2WW. Clinic told me to test on Tuesday. Fingers crossed we both get positive results xxxx
Thank you, I did think this but I spoke to them yesterday and they said just to carry on as normal with the two!
I might just try it though if it won’t do any harm!!
The bleeding is neither here or there, one minute I think it’s gonna come heavy then it’s like hardly there!! So strange! When we had our chemical the bleeding was full on heavy by now so I’m so confused xxx
Hopefully it does if you haven't got a full bleed but it may not be enough now. But Def for future make sure they review that! Recurrent bleeding should be treated with higher progesterone and maybe even injections for better absorption as dose might be ok but absorption not.
I'm now on lubion injections as others are and pessaries too
I think yours are strong though Lisa, bear that in mind, yours are 400 each aren’t they? I’m on 3 a day but they are 200 each, so you’re technically on 4 a day as I think most people’s capsules are only 200mg each? X
Do you ovulate normally and have regular periods generally?
Would you get any spotting in between periods when you were menstrusting ?
If these issues came up before then it's Def worth asking your clinic and upping your progesterone
Otherwise it may be perfectly fine for you to carry on! So don't fret.
However usually if there's multiple failed cycles I do believe they often up progesterone a little so depends if you've been on same protocol (and same pessaries? Before)
But certainly if you often bleed (red blood and flow not necessarily OCC brown blood that may be from implantation- but can also be low progesterone too ) and early on in transfers I would definitely bring up progesterone support and changing to injections rather than pessaries alone at your next follow up.
I was on the same dosage of pessaries for my first ivf transfer and came on my period on day 8, so for my last 3 transfers I’ve used IM or lubion injections, but as they are a few hundred quid more expensive, I’ve gone back to pessaries now for my 5th transfer, first private. Same clinic, same protocol, no changes at all...which is why I’m worried about coming in early again and due to lots of failed transfers like you say it may be worth upping my dosage x
Hi Scarlett - only you can make that decision along with your clinic.
But if they already gave u lubion previously and you didn't bleed it would make sense to me to up your pessaries at the very least.
Have you had any cramping so far? If not I don't really see the harm in doing so as a preventative measure rather than waiting for a break in the lining which may be too late (as it was for me 😪)
You haven't said what type pessary youre on? I only have experience of utrogestan and cyclogest.
Also we naturally produce less hormones ourselves as we get older- oestrogen also- so you should be on support for both i believe?
They usually give both for 2ww.
It may be the progesterone 'dose' varies between different types of pessary so worth asking your clinic.
Sometimes rectal absorption works better than vaginal also.
Do you have any other hormonal or health issue? Pcos/thyroid/endometriosis ?
I’m on utrogestan 200 x3 daily. I’m 38. Not on any oestrogen support, never been mentioned actually. I had mild endometriosis ablated during a laparoscopy. No other concerns. I have blocked tubes, good AMH. I’m on metformin and DHEA. Never had thyroid tested. No pcos.
Cramping has started just today, 7dp5dt. Thanks for your help! X
That is one of the biggest factors in infertility and early miscarriage and it's shocking how many clinics don't test it still whilst others won't even let you start until it's controlled.
It is worth having it tested asap as if you are hypothyroid you will need thyroxine treatment soon and as soon as you are pregnant as your baby relies solely on your thyroid hormone especially first trimester.
Normal thyroid TSH result should be below 4.0
But if you are TTC then it should be below 2.5 and then increased again once pregnant by 25mcg.
NICE guidelines state this (and NHS follow their guidelines but a lot of GPs are still unaware so you may want to mention it.)
I don't want to worry you so please don't stress but as it's something that can be easily tested and treated straight away you may aswell get tested at doctors in meantime
Regarding pessaries If it was me I would up it straight away. I'm sure lots of ladies on here with endometriosis also said they upped progesterone too. If the cramps stop great. If they continue you may want to up again as 200mg 3x day is isn't high.
If you look at HFEA website they say progesterone is the safest added intervention you can take but obviously please do your own research and do what you feel comfortable with.
I just try and raise awareness of something when I see it so at least we're not left in the dark.
Are you not taking any oestrogen/oestradill at all? Evorel patches? Progynova tablets?
Never had thyroid tested ever, maybe as blocked tubes is my reason for not being able to get pregnant it wasn’t something thought of? But I’ll ask my GP! Thanks for this info x I’m going to up to a 4th pessaries from today then ring my clinic about it on Monday. Not on any oestrogen. I did take progynova when I did my FETs to get my womb lining thick enough but I think that was only up until embryo trabsfer. With my fresh transfers my womb got thick enough with the ivf drugs. Menopur, fyremadel and trigger I took. Apart from pessaries the only other meds I’m on is DHEA until OTD and metformin until OTD. X
I'm not as familiar with diff protocols on oestrogen supplements but I know many of us are on it throughout 2ww and further also.
If you have low.oestrogen levels and poor ovulation pre IVF generally I think they give oestrogen as well as progesterone as that is what the body would normally produce. (However Metformin is also used to control insulin resistance and oestrogen binding issues so maybe that's helping.)
That may also be why they are happy with a low progesterone support as no oestrogen?
Tbh sometimes it feels they just guess a number they're comfortable with and stick with it until it fails multiple times!
But certainly you would only produce progesterone when you are pregnant naturally or at time of ovulation..
After a fresh transfer and after egg collection the cells that make progesterone as well as the eggs are removed from your body (I read in an article) so high progesterone is definitely needed.
Ooh exciting! I have 2 in this time (for the first time too). Sounds like you have done so much research, are in good hands, and have done everything that you can - I wish you all the best for Xmas eve xxxx
Thank you.😌 I feel better knowing we've done all we can
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Wish you luck too xx
Gosh it really is a roller coaster - keep going - less than 24 hours tomorrow - I am so in awe of your determination resisting testing. Good luck lovely xxxx
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