Pcos

[Amieex]

I have been have pcos for a while now, have been getting weight down for bmi, haven't had period im over 6 months, doctor start me on metformin 2 tabs a day (1000mg) what should I expect now? From the tabs? Desparate too conceive Thanks xx

[Princess09]

Hi Aimeex,im in the same boat as you but a bit further down the line.my periods were very irregular too,I was going months at a time and desperately trying to conceive.i have a little boy whos nearly 5 who I conceived naturally and got pregnant again a couple of years ago but had a miscarriage.ive been on metformin 1000mg since feb and my periods were between 5-8 weeks but I wasnt ovulating.ive been on clomid now for two cycles and im hoping we get lucky.wishing you lots of luck,I know how frustrating it is.here if you want to chat.xx

[Amieex in reply to Princess09]

Hey Princess09, thank you for the advice, yeah my period is like that also, at times I don't have it atol, so I don't ovulate, I've been referred too infertility clinic, have too get my BMI down which I am doing so, I started metformin around 2 1/2 weeks ago had slight bleeding a week ago, im hoping metformin does something for me, yes it's very frustrating xxx

[AndiK73]

I went from no periods to a 35 day cycle in around 3 months when I started on met (500mg x 2). Expect a few very heavy periods when you get them back. Good luck

[P_willy]

I didn't have a period for years due to pcos. I was on clomid and then menopur, they made me have periods but I wasn't ovulating. I decided to lose weight, 2.5 stone, and my periods came back on a regular 35 day cycle. The dr said my weight wasn't an issue but clearly it was!! Good luck x

[DianeArnold Partner Nurse Fertility Network UK]

Hi Amieex. I don’t know if you know much about how Metformin works, but just thought I would explain as simply as I can, with apologies if you already know. People who are diabetic (I realise you are not) - are treated in 3 different ways – diet, tablets (Metformin) or insulin injections. Women who are not ovulating properly and/or do not have regular periods and who are overweight, are often prescribed Metformin. The reason being is that they often have an excess of insulin in their body cells. Because of this the glands in the brain that control ovulation, the pituitary and the hypothalamus cannot get their message through to the ovaries to get them to ovulate properly. Metformin “mops up” the excess insulin to allow the messages to get through. Often it can regulate periods, but ovulation still does not occur. This is when a drug called Clomid is often introduced as well to hopefully ensure ovulation occurs. Metformin allows Clomid to do its job more efficiently. It all sounds very complicated, but the mechanics of the idea work well. Of course this treatment does not work with every woman, and there is always the possibility that IVF or similar treatments may be required. Obviously, I do wish you well with the outcome of your treatment. Diane

[peakpaw]

Very informative