MRE vs Fibroscan: I had a fibroscan... - Living with Fatty...

Living with Fatty Liver and NASH

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MRE vs Fibroscan

Summtyme profile image
18 Replies

I had a fibroscan done last month with a 17 Kpa (cirrhosis). Bloodwork is perfect. They did the fibroscan because 6 months ago I had an ultrasound that showed a slightly enlarged spleen and some fatty infiltration in the liver. They are sending me for an MRI with elastography on Friday to confirm the staging.

Does anyone have any experience with this test? Is it more reliable than the fibroscan?

I’m not a drinker at all. Frankly I’ve been in shock over the fibroscan diagnosis. I was 20 lbs overweight but I’m already down 12 pounds.

Is the MRE reliable? Your experiences would be a big help to me.

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Summtyme profile image
Summtyme
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18 Replies
MINTVCX profile image
MINTVCX

I think you cannot say that fibroscan is less reliable than MRI with elastography. Also you cannot be diagnosed only with fibroscan result. Like any other test fibroscan can be false positive.

Good hepatologist takes into account all tests (imaging, blood, symptoms, age, risk factor like overweight, family health status, gender etc.). So I think you have to calm down and wait for futher tests that your doctor would order. Unfortunately no simple path to diagnose liver issues sometimes. Good luck.

nash1996 profile image
nash1996

My hepatologist says that fibroscans usually have a tendency to overestimate rather than underestimate. Lots of things can influence the accuracy of the reading, such as a high BMI, high liver enzymes, whether you fasted or not before the scan. In my case my score was a stage 3, but my liver biopsy lowered this to a stage 2. My fibroscan has since come down to a stage 2 now that my enzymes are lower. I've never been offered an MRI with elastography. I've had an a liver ultrasound, a fibroscan and a biopsy.

ThyroidDeb profile image
ThyroidDeb in reply to nash1996

My hepotoligist said no reason for MRI elasticity since I had biopsy. 🤷‍♀️

nash2 profile image
nash2Partner

MRE is currently considered to be the best non-invasive measure for fibrosis. It is similar to FibroScan but looks at the entire liver not just a small section.

MINTVCX profile image
MINTVCX in reply to nash2

Indeed at least for NALFD:

"In a prospective, cross-sectional study of more than 100 patients, we found MRE to be more accurate than TE in identification of liver fibrosis (stage 1 or more), using biopsy analysis as the standard."

ncbi.nlm.nih.gov/pmc/articl...

Interesting:

" MRE Plus Fibrosis-4 vs FibroScan-AST in Detecting NASH-Related Fibrosis"

practiceupdate.com/content/...

waterstop profile image
waterstop in reply to nash2

do mean MRI? I have not heard of a MRE. Thank you for your answers.

nash2 profile image
nash2Partner in reply to waterstop

MR elastography is a specialized form of MRI than measures liver stiffness

waterstop profile image
waterstop in reply to nash2

So is that essentially the same thing as the Shear Wave Fibroscan which demonstrates the liver stiffness (4,9E kPa......my result ) and I believe the amount of liver fat (309 ACE dB/m........my result) which gives one the CAP score( Controlled Attenuation Parameter), which in turn, determines the S score?. If this is all wrong, please advise as I had to research this myself. Thanks so much. You can bill me for your knowledge!!!!!

nash2 profile image
nash2Partner in reply to waterstop

Yes, they measure the same thing in terms of stiffness though their result ranges are different. The fat fraction with MRI is calculated with proton density fat fraction PDFF and reports as a percentage.

waterstop profile image
waterstop in reply to nash2

Thanks for clearing that up.

Pita123 profile image
Pita123

I did mine last week and got the results today. My doctor thought it was a more reliable test than the ultrasound and the fibroscan. More convenient and covers more of the liver than a biopsy. It took a little over one hour since they did it with and without contrast. I am not claustrophobic but it was not very easy. Be prepared for it and you'll be fine. My doctor is using the MRI results as his guide for our treatment moving forward. My report also showed how some of the other organs are looking. Good luck and don't worry too much!

2BHealthy2022 profile image
2BHealthy2022 in reply to Pita123

What treatment? I was told other than diet and exercise there is no treatment?

Pita123 profile image
Pita123 in reply to 2BHealthy2022

Correct. No medical treatment. Just our way forward and frequency of future tests as I improve my diet and weight. Best wishes for tomorrow!

Summtyme profile image
Summtyme

Thank you so much for your experience. I wish you the best in your treatment.

Alterity profile image
Alterity

In my opinion the MRI with Elasticity is by far better than just a fiberscan. It may take an hour or 2 to do, which was rough for me because I was one of the first people to have one at my hospital, where the Fiberscan takes minutes, That tells me the MRi with Elasticity is more through and I would love to have one again. Good luck.

Liver007123 profile image
Liver007123 in reply to Alterity

Iam having a MRI with contrast is this the same sort of thing My fibroscan was extremely high and was diagnosed with Cirrhosis secondary to NASH this was told to me in a letter 🤦🏼‍♀️🥺

Summtyme profile image
Summtyme

Update. My MRE results came in!! The cirrhosis diagnoses was walked back!! I have a mild fatty liver. I just cannot believe it but am so grateful. Hepatolgist says the MRE is the results to believe although last month he felt the fibroscan was a solid reading of 17 kpa since the IQR was only 9%.

He feels I’m in the clear and to retest in 2 years.

andrewax2 profile image
andrewax2 in reply to Summtyme

Glad to hear that! The MRE was also very useful for me.

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