Zoladex without HRT what are your goes to... - Endometriosis UK

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Zoladex without HRT what are your goes to supplements and natural approach to help with the initial flare up and the menopause symptoms?

happyseal profile image

Hi ladies,

I got my first shot of Zoladex on Monday and within 5 days I'm having acne breakouts, horrible flare up of Endo with more pain etc, migraines, night sweats that keeps waking me up, my bowels can't stop working and hurts a lot, horrible mood swings, and all this during my period.

I will be on zoladex for 4-6m before surgery for fertility so I won't take any HRT during this time. Any advice on how to manage the initial flare up? And how to manage the menopause symptoms?

Thank you 💟

17 Replies

Hello! I had 10 injections (5 months without HRT). Hot baths with epsom salts, heat packs, ice packs, fan and telling those you interact with what you’re going through so they understand if you seem low/depressed. For the insomnia, I just try to sleep when I can and don’t guilt trip myself when I can’t.

Gilena profile image
Gilena in reply to Gilena

Regarding the initial flare up, I have no advice because I ended up in the emergency room with a morphine IV. Pain was significantly reduced/gone after the initial flare up.

happyseal profile image
happyseal in reply to Gilena

That must've been a terrifying experience. Thank you for sharing. Did you change anything in your diet to up Vit D, calcium etc?

Gilena profile image
Gilena in reply to happyseal

I am eating more calcium (milk, cheese, yogurt) now. Didn’t change anything else…

You will get a flare up as oestrogen levels rise sharply before the ovaries shut down. It can take around 3 weeks to settle.

happyseal profile image
happyseal in reply to Lindle

Yes I'm feeling it. So uncomfortable 🥺🥺🥺 I'll probably add some fasting and up fiber to help clear the excess estrogens.

You will need to check with maybe your doctor or pharmacist but Sage Tablets can help with hot flushes. If you are UK based you can get them in Boots usually on offer three for price of two.

Acne I just changed my skincare routine to more gentle products, it’s calming down slowly. I’m on shot 2, without HRT I feel tired and bloated after and just ride the insomnia wave. Good luck

happyseal profile image
happyseal in reply to BeeHoneyB

Yep the insomnia doesn't help my energy. Thank you for your suggestions. Do you take sage every day then?

BeeHoneyB profile image
BeeHoneyB in reply to happyseal

Insomnia is awful I’ve reduced my coffee intake to only morning as I was getting reliant on it to keep me going. Yes I was taking the sage tablets every day. I’ve stopped now to see if they have calmed down the flushes so far so good!

I stopped taking my combined pills few days after the Zoladex injection by doctor's order. I had same symptoms, infact worse. My doctor explained that it was withdrawal symptoms(because I stopped the pills) coupled with menauposal symptoms(because of the Zoladex). So I advise you talk to your doctor and explain your concerns. Above all relax and enjoy life dear🥰Find coping mechanisms that helps your body and everything will take it's natural course. Stay positive.

happyseal profile image
happyseal in reply to Elspy1

Heya, How did you manage your symptoms?

I wasn't on contraceptive pills. So it's just the flare up. I'm positive things will get better after a month and I'll probably just have the zoladex menopause symptoms.

My period have finally ended so most of the pains have subsided, which is good.

I used to take herbal sleeping pills - valium based, and primrose oil. It helped a bit with mood swings and hot flushes. Or maybe my body just got used to it? I was on prostap for 6 long months...

happyseal profile image
happyseal in reply to Buisquits

Hello,Oh I didn't know primrose oil helps. I do take it daily already. How much do you take daily?

I'm taking magnesium and 5htp before bed and it seems to be working.

I'm meant to stay on it for 6months, but hopefully I don't have to, it depends how the waiting list is.

Buisquits profile image
Buisquits in reply to happyseal

I guess it was 1000 a day. The pills are quite big and tricky to get down. Prostap has a massive impact on me. I go mad. Hopefully your waiting list won't be too long x

happyseal profile image
happyseal in reply to Buisquits

I feel you... I have been crying out of nowhere 😭 without any reason all the time. So weird...

Buisquits profile image
Buisquits in reply to happyseal

I was reading Stickman today and the tears just started coming 🤣

happyseal profile image
happyseal in reply to Buisquits

Haha 🤣🤣

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