New treatment for early CKD news!!! - Early CKD Support

Early CKD Support

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New treatment for early CKD news!!!

Marvin8 profile image
Marvin8

This medication news could be HUGE. Fingers crossed that it turns out to be as effective as is claimed in the studies.

medpagetoday.com/nephrology...

27 Replies

Not a new treatment as such as it has been around since 2014. It also has serious side effects in some people - many of which have proved fatal. I would want to know much more about this drug before taking it!

Yes, is primarily for T2D, but if I recall correctly, they stopped the trials early due to the outstanding benefits for both T2D and ckd. It's not so great for those with polycystic ckd and a few other confounding conditions, but it sure looks promising to me. It's a whole new class of diabetic treatments that provides hope to some of us looking to slow the progression of ckd. Will be darned curious to hear my neph's take on it.

userotc profile image
userotc in reply to Marvin8

Personally I think it's a shame that drugs are being considered for conditions that can be managed and even reversed naturally, particularly with a history indicated by Buspasswalker. But no surprise that profit-driven, drugs companies are in the frame!

Marvin8 profile image
Marvin8 in reply to userotc

I'm certainly no lover of the pharmaceutical industry, but I must challenge you on your assertion that ckd can be reversed naturally....or at all. Please show me scientific evidence of ckd patients growing new nephrons. It would be wonderful if stem cell research had progressed that far, but it hasn't.

SkiingSailor profile image
SkiingSailor in reply to Marvin8

Whole kidney tissue can’t regenerate, you can massively improve the filtration rate with diet and exercise of your doctor chooses to tell you about your CKD. Mine’s gone from 51 to 83 since Nov 2020 .

Marvin8 profile image
Marvin8 in reply to SkiingSailor

That's fantastic. Congratulations!

RickHow profile image
RickHow in reply to Marvin8

People report they reversed the CKD but they fail to report why they were labelled as having CKD in the first place. For example, diabetes, kidney stones, blockage, tumor, medications, on and on and on can cause one to get a low egfr and thus be labelled as CKD. But then these medically caused reasons are "fixed". They see an improvement in egfr and think, "ah, I reversed CKD". I've read many posts of those who drink excessive amounts of water for 2 or 3 days in a row before a blood test. They get an improved egfr. Think they reversed/improved their kidney function. It just isn't so.

My rate also went from 51 to 80, I thought at first it was such a big (pleasant) jump that it must be a mistake. I have been drinking more and watching my protein intake, apart from that not a lot of change in my diet, so I am curious Ski Sailor - how did you achieve such good results and can you offer any advice how to keep such good levels

That's a phenomenal increase. Congrats!

I have to admit to falling off the wagon recently, since the blood results. I followed Lee Hull’s book “ Stopping Kidney Disease “ went vegan, reduced processed foods, drastically reduced my chocolate ( addiction) and all was well.

I need to get back on the wagon food wise, but harder now that the economy is opening up again and we can all get out and about again.

Good luck.

That is good mine has gone from 55 to 72 with diet change .

But the newest thought is that kidneys can in fact heal maybe not totally but quite a bit . So keep up the good work and smile .

userotc profile image
userotc in reply to Marvin8

The reversal was in reference to T2 diabetes. The management was for CKD - I presume no argument there?

Marvin8 profile image
Marvin8 in reply to userotc

None whatsoever. :)

RickHow profile image
RickHow in reply to Marvin8

well said Marvin. If CKD could be so reversed naturally every kidney doctor in the world would be giving that method to their patients.

Marvin8 profile image
Marvin8 in reply to RickHow

Do you really think so, Rick?scientificamerican.com/arti...

RickHow profile image
RickHow in reply to Marvin8

Hi. I went to your link. I miss the point. The link is about dialysis and how centers developed, etc., etc.

Marvin8 profile image
Marvin8 in reply to RickHow

The article is about the opaque financial stake nephrologists have in dialysis centers. Dialysis centers rake in approximately $90,000 per year per patient and most nephrologists are part owners. The two nephrologists I've seen both have stakes in their dialysis centers. That's where the money is made, not in office visits. You said that if CKD could be reversed naturally, every kidney doctor in the world would be giving that medication to their patients. Your statement assumes if all nephrologists were faced between their own financial health versus the health of their patients, they'd choose the latter.

RickHow profile image
RickHow in reply to Marvin8

Thanks for making your point clearer.

News like this is always eye catching. Apparently there are two medications - Farxiga and Jordiance - in the horse race to capture the CKD market. Farxiga has pulled ahead in getting US FDA approvals; I predict Jordiance won't be far behind. It's my understanding that these products slow progression, but won't repair the kidneys. As a caregiver to my diabetic hubby who has taken multiple medications to control his diabetes (type 2) and prevent the progressive kidney damage that has since led to dialysis - there truly are no magic cures out there in my humble opinion. And I sense many (including hubby) have relied on pharmaceuticals to bring them to a ripe old age and, sadly, many have failed. (It's the blithe old saying, "Simple! Just pop a pill for that - snap fingers - it goes away!") Yet, I sincerely do hope these medications will help moderate the disease process for those facing CKD, and I also hope that the side effects don't lead to other issues. As always, I urge everyone to eat healthy, exercise daily, enjoy life in good ways now and down the road. Life is precious.

SMM62 profile image
SMM62 in reply to Darlenia

Jardiance is horrible for kidneys

Marvin8 profile image
Marvin8 in reply to SMM62

Not according to the studies. Is this anecdotal evidence you're speaking of?

SMM62 profile image
SMM62 in reply to Marvin8

My husband took it. Right on the packaging it says that it can cause kidney failure

Marvin8 profile image
Marvin8 in reply to SMM62

Well that sucks to hear. :(

Maybe , but with so many of these new meds they are always side effects sometimes bad side effects . So go slowly and be careful.

Agreed!

My husband who has type 2 diabetes took it for a while. He got serious side effects and had to stop. It also did nothing for his diabetes and his blood sugar rose while on it.

hi does anybody used Tolvaptan?