Protein in Urine.

I am diabetic for 35 years. my Bliod sugar satisfactorily maintained. Except for few fluctuations. Medication is Glimepride 1 mg in the morning. If the reading is unfavorable Metformin 500 mg added before bed. Otherwise, FBs below 115 And PP 140-180.

Now the latest test shows protein +30 in urine. I am also taking 50 mg Losartan daily for my Blood Pressure. Blood Pressure is under control. It is consistently at 120/70 and 130/80. I do not want to increase anymore Losartan. Is there way to get this issue corrected. By the way my ultrasound scan says two kidneys are in order. But fatty liver is grade 1.

Can anyone help me .


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14 Replies

  • advisable to consult nephrologist for protein discharge in urine.

  • Seems like diabetes is better - you are at beginning stage - do more exercise and follow LCHF diet - reduce carbs to less than 100 grams per day - may help lot

    For BP- take aged garlic and L- carnitine ( or L- Arginine ) - supplements - available at Health Food store or Vitamin shop in USA -

    For urine and fatty liver - search - here and wait for Anup or other experts to reply

    Good luck

  • He is diebetic since 35 years

  • yes - but he says - under control.

  • Each kidney is made of hundreds of thousands of small units called nephrons. These structures filter your blood, help remove waste from the body, and control fluid balance.

    In people with diabetes, the nephrons slowly thicken and become scarred over time. The nephrons begin to leak and protein (albumin) passes into the urine. This damage can happen years before any symptoms begin.

    Glimepiride is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally.

    Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Metformin is in a class of drugs called biguanides. Metformin helps to control the amount of glucose (sugar) in your blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood.

    Losartan is used alone or in combination with other medications to treat high blood pressure. Losartan is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). Losartan may not decrease the risk of stroke in African Americans who have these conditions. This medication is also used to treat kidney disease in people who have type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) and high blood pressure. Losartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

    Once fatty liver is diagnosed, the important things to do include weight control, control of diabetes if present and control of lipids.

    Fasting blood sugar should be less than 100 mg/dL.

    Postprandial blood sugar (2 hours after taking food) should be less than 140 mg/dL.

    HbA1c should be less than 6.5%.


  • Mr- Gangadharan-- you give info - Theoretical- but not giving any suggestion - to help him. there is insulin resistance -and can NOT effectively

    If Glmpiride-- produces more insulin- what good it is --if there is RESISTANCE and can NOT effectively use it.. sugar stays in blood.

  • Ravees -- what was your A1C - last six to nine months ?

    Seems like you have too much- high sugar - spikes. PP of 180 is also high

    You may have nerve damage and kidney is not working effectively -- even though eGFR

    may be okay - still better to see a Nephrologist.

    Also may check with neurologist to do ABI test -- and check eyes - for Retinopathy.

  • Thank you. My test is due next week. I would be able to give present position when zi get the reports.

  • yes- but you should have previous two readings -- A1C is done every three months. Just curious

  • Both readings were 7.0

  • Really - that's A1C ? then its okay - may be some different problem --

    need to see kidney doctor -

  • Ravees - IF you are in USA --please check my post - just posted - about DKD

    study --

  • Ravees

    Is it protein or micro albumin ?

  • There is no allopathic medicines to reduce protein in urine but in homeopathy there is but u need to consult good homepathic doctor

    I will tell u name of medicines but don't take on your own pls

    Name of medicines is R64 (Dr.reckweg product) take after discussing with homeopathic doctor u can continue all other allopathic medicines with this homeopathy medicines u need to consult homeopathic doctor for dosage

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