Early Life Origins of Insulin Resistance an... - Diabetes India

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Early Life Origins of Insulin Resistance and Type 2 Diabetes in India and Other Asian Countries

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cureAdministrator
16 Replies

jn.nutrition.org/content/13...

There is a rapidly increasing epidemic of type 2 diabetes in India and other Asian countries. The thrifty genotype and the thrifty phenotype are two nonexclusive explanations. People in the Indian subcontinent have faced undernutrition for many generations, and Indian babies are among the smallest in the world. However, the diabetes epidemic is of recent origin, and diabetes is more common among urban than rural Indians despite the higher birth weight of urban babies. This suggests that postnatal factors must also contribute. Thus, a life-course model of evolution of insulin resistance and type 2 diabetes, incorporating fetal, postnatal and adult components, seems most appropriate. For a given BMI, Indians have a higher percentage of body fat and more visceral fat than members of other populations.

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bhanjois72 profile image
bhanjois72

"This suggests that postnatal factors must also contribute. Thus, a life-course model of evolution of insulin resistance and type 2 diabetes, incorporating fetal, postnatal and adult components, seems most appropriate"

The above statement is not clear.Can the administrators elaborate what they mean

cure profile image
cureAdministrator in reply tobhanjois72

This means we are still trying to understand the cause of insulin resistance and D2... :)

suramo profile image
suramoStar in reply tocure

cure

Has that anything to do with high carb vegetarian diet ? It's said that wheat is not our original food. Wheat had been brought from outside. Our staple food is millets etc.

kkmworldno1 profile image
kkmworldno1 in reply tosuramo

Yes, as per some recent naturopaths. They very much say that millets were and the best food of ours in India. only when later the Rice was added by the then rich people. Even then, but also due to hard working life styles and culturally very traditional polishing of rice, was some what better instead of mechanically polished WHITESET rice. WHICH IS THE CULPRINT AND SEDENTARY LIFE STYLE. Whatever, all discussed argued, debated, and what not...ultimately this is the reason for diabetes.

Now there is some craze going on for millets, and now the low income people not getting millets due to price hike.

bhanjois72 profile image
bhanjois72

Are millers low carb?

shrisamarth profile image
shrisamarthVolunteer in reply tobhanjois72

No. Most millets are around 70% carbs.

cure profile image
cureAdministrator in reply toshrisamarth

but guess millets are not GMO grains....

shrisamarth profile image
shrisamarthVolunteer in reply tocure

I think main GMO crops are corn and soya.

Millets are not GMO.

cure profile image
cureAdministrator in reply toshrisamarth

even wheat is GMO.... and guess what??? even Long wheat which we get at present is also GMO :d

shrisamarth profile image
shrisamarthVolunteer in reply tocure

Long wheat which we get at present is also GMO

:D :D

AFAIK wheat and rice is not GMO Commercially). Only natural and artificial hybridization.

Full genetic mapping of wheat is not yet done.

cure profile image
cureAdministrator in reply toshrisamarth

look at the process how they modify the height of wheat plant...by bombarding it with some gamma rays...

shrisamarth profile image
shrisamarthVolunteer in reply tocure

hmm :(

cure profile image
cureAdministrator in reply toshrisamarth

Dharwad university... and Agharkar institute are main culprits....

suramo profile image
suramoStar in reply tobhanjois72

No. High fibers. Especially siridhanya millets.

bhanjois72 profile image
bhanjois72

does Gm make a millet low carb or high carb."

shrisamarth profile image
shrisamarthVolunteer in reply tobhanjois72

No.

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