Can diabetes or pre diabetes be prevented or delayed ?

[patliputra]

Any thoughts.

[norreal]

The key is 'diet'. Type II can easily be delayed if not prevented.

[patliputra in reply to norreal]

How to assess and forecast that one is going to suffer from type 2 diabetes ?

[MRA13]

I think the Key is yet to be identified.

Read these please

Intramyocellular accumulation of toxic lipid metabolites play an important role in the pathogenesis of muscle insulin resistance

ncbi.nlm.nih.gov/pmc/articl...

These data lend further support to the observation that insulin resistance in skeletal muscle is an early metabolic defect in the pathogenesis of type 2 diabetes and that muscle lipid accumulation plays a central role in the etiology of the muscle insulin resistance.

It is unclear which is the cart and which is the horse: mitochondrial dysfunction leading to increased intramyocellular lipid content and insulin resistance or increased muscle lipid content (i.e., secondary to elevated plasma FFA levels and/or excessive lipid ingestion) leading to mitochondrial dysfunction and insulin resistance.

----- ------- ---------

Now the next is about lymphatic circulation which transports Free Fatty Acidd, is moved along by muscle contractions and if not allowed to drain, would deposit toxins and fats in the muscles.

ncbi.nlm.nih.gov/pmc/articl...

The last exercise of Dr MV Prasad is the one generally advised, besides jumping on a trampoline and dry body brushing, for lymph movement.

So 80% glucose uptake is in the skeletal muscles. As for

Skeletal muscle exercises

physrev.physiology.org/cont...

Here something called GLUT4 comes in.

So Sri Sri and Ramdev's stomach breathing, Dr. Prasad's exercises and bouncing all activate the lymphatic system that has long been neglected.

Shooter George's ancient wheat puts us back on resistant starches which even affects the meals that follow. After yesterday night's long wheat, today I had rice noodles for break fast and cassava and sama lunch. Yet with just 16 units of insulin ( where it was 26 about 10 days back) PPBS remained 150.

Is a compromised lymphatic system, the shadowy parallel circulatory system the key? It is also the key player in our immune response and diabetes is also considered an auto immune disease. Could a disgruntled, neglected Thymus and spleen be raging at us through diabetes?

Peace! Shalom! Shanti !

Can we make resistant starch meals from modern wheat? Can we do better and conscious deep breathing? Dance a bit to move the chile and please the child in us ?

[patliputra in reply to MRA13]

That was highly scientific explanation covering many aspects of diabetes and its management. But that may not be understood by many,

By the way, I was I who gave scientific basis to SG' s long wheat and brought emmer wheat to this forum. It was also I who high lighted resistance starch and its properties.

Prevention of pre diabetes depends on how we can predict that some body is going to suffer from pre or full diabetes and what measures needs to taken ,these were the broad points, which need to be discussed, though you have touched a few points.

Thank you.

[MRA13]

Chronic stress. So stress control is another requirement.

[patliputra]

I agree that both heredity and life style,which include apart from other things also include nutrition and physical activities,may have predictive value. But we must remember that heredity do not by itself cause a disease and same is true for life style. These are predisposing and precipitating factors. Agreed. We know we can not change heredity,so only life style changes remains. It is common understanding that an active life with a proper healthy meals with healthy habits AND a sound good night sleep is good for healthy life.

But how to find that some thing is amiss and that may lead to pre or full diabetes. Can some thing be done ?

It is well known fact that before diabetes or pre diabetes is diagnosed,it's seed is sown many decades earlier. If at that time or the earliest changes is detected then it is possible to prevent its progression or even its reversal is possible.

[patliputra]

Researchers now agree that level of blood insulin starts rising 10-20 yrs. before one is diagnosed pre diabetic or a diabetic . So it is possible to monitor level of insulin and blood glucose levels to see if there is rising tendency in insulin levels even if bs is within normal limits. If that is the case it can be presumed that it can lead to to pre diabetic stage. At this stage measures can be taken to off set this hyperinsulinemia and eliminating the possibility of diabetes and well as other metabolic diseases,etc.

[patliputra]

People eat food and not carb,fat or protein. For a common man it is very difficult to know high or low gi or that matter any of these things . If you look out side these forums ,even educated persons don't understand these things.

[patliputra]

True,what you say is true. But fact is scientific advancement takes time to be translated into practice.so I will not blame health professionals,they are only suggesting what has been taught and followed universally. If an idea is engraved in people's mind it takes long time to change it. And it could be done only by repeatedly explaining in detail to create an awareness to be followed by acceptance.

[patliputra]

It is correctly mentioned by all that hyperinsulinemia is the result of insulin resistance. How insulin resistance occurs is a very complicated issue as well as a matter of debate as it is yet to be clearly understood . But there seems to be general agreement that inflammation may be the cause. Why and how inflammation occurs is difficult to say but people are saying that it is oxidative stress which is responsible for inflammation . Apart from other factors it is high level of circulating free fatty acid and high blood glucose levels that increases the level of oxidative stress and every thing moves in a vicious circle.

Yes, high levels of fructose do cause insulin resistance ,but it is confined only in the liver cells. At same time it is high intake of sugar which is responsible and not the fructose contained in fruits.

It is healthy regulated life style combined with healthy diet and physical activity can prevent or delay not only diabetes but also many chronic diseases ,CHD and BP Alhzimer,Arthritis etc.

[patliputra]

I agree with you.but a general screening may not be possible ,but it is possible to suggest fasting and pp bs and insulin along with other blood tests. In this way hyperinsulinemia can be detectected at an early stage where prevention may be possible for many diseases.

By the way insulin measurement can be done and is available at most of the path. labs.

[patliputra]

It costs Rs 500 ,where I live.

[patliputra]

Fructose metabolism is very complicated issue. Dietary fructose is ingested not alone but with other saccharides. It is a subject of debate,perhaps later. Thank you.