Treating Parkinson’s by targeting the gut... - Cure Parkinson's

Cure Parkinson's

26,186 members27,514 posts

Treating Parkinson’s by targeting the gut-brain axis with B vitamins

Farooqji profile image
9 Replies

A study by Nagoya University in Japan found a link between gut bacteria and Parkinson’s disease (PD). Researchers discovered fewer gut bacteria genes that make B vitamins B2 and B7 in PD patients.

They also found that low levels of these vitamins are linked to poor intestinal barrier function, allowing toxins to enter the bloodstream and cause inflammation in PD.

techexplorist.com/treating-...

Written by
Farooqji profile image
Farooqji
To view profiles and participate in discussions please or .
Read more about...
9 Replies
JayPwP profile image
JayPwP

Can it be so simple?

Esperanto profile image
Esperanto in reply to JayPwP

Yes, for some of us, it can indeed be that simple... From my own experience, I can say that with the necessary supplementation of B vitamins, including B2 and B7, the improvement in my PD symptoms has been spectacular. This research provides a basis for the possible mechanisms involved. Although (not yet) a cure, it is very promising to experience a potential inhibitory effect on PD with a balanced intake of Vitamin B over the longer term, with normal dosages!

JayPwP profile image
JayPwP in reply to Esperanto

I understand supplementation... I am referring to the reduced bacteria. Is the reduced bacteria the cause or the result of PD?

Esperanto profile image
Esperanto in reply to JayPwP

The study highlights an association between gut bacteria and PD, but it doesn't definitively establish whether the reduced bacteria are a cause or a result of PD. There's even the possibility of a bidirectional relationship where changes in gut bacteria and PD influence each other in a cycle. Such associations often lead to further investigations to determine causality… However, adjusting gut bacteria levels might delay the onset of PD symptoms. Supplements of vitamins B2 and B7 seem crucial in this process.

goldengrove profile image
goldengrove in reply to Esperanto

Do you take B2 and B7 supplements or a B complex that contains them among others? And can you please specify dosages.

Esperanto profile image
Esperanto in reply to goldengrove

I alternate the supplements daily with:

(Day 1) Low-dose B-complex with 2.8 mg B2 and 0.125 mg B7

(Day 2) Moderately dosed multivitamins with 20 mg B2 and 0.120 mg B7

(Day 3) separate vitamins and minerals for correction, including an additional 79 mg B2 and limiting the intake of B12, P5P (B6), and folate (B9).

park_bear profile image
park_bear

Vitamin B2 deficiency commonplace and consequential: healthunlocked.com/cure-par....

Pixelpixie profile image
Pixelpixie

what dosage of B complex works for you?

gomelgo profile image
gomelgo

So grateful for all your posts. 🙏

Not what you're looking for?

You may also like...

B Vitamins and the Brain: Mechanisms, Dose and Efficacy

B vitamins are essential for brain function and are generally safe to consume in higher amounts...

Need to separate types of PD

This is a hypothesis that might explain contradictory data related to PD: Quote: Here, it...

PD Paradigm shift: Brain-First versus Gut-First Parkinson’s Disease: A Hypothesis.

An important hypothesis about PD origins was recently published. The abstract conveys the...

Interesting article on probiotics and the gut-brain link.

It appears that an abundance of bad probiotics in the gut can help alpha-synuclein proliferate....

Doctors use levodopa responsiveness to diagnose, but a new report today says a specific gut bacteria prevents it from getting to the brain

I often feel I am sometimes unresponsive to levodopa. I wonder if these bacteria come and go. In...