I have horrible tremors of both Legs, Hands, Head, Hips, RMS of all body parts, and PMLD. I am managing with KAPIKACHUU, a natural Dopa. I can manage from 7.00 am up to 12.00 Noon, thereafter, I will experience, horrible tremors of both Legs, Hands, Head, Hips, RMS of all body parts, and PMLD. Please suggest me how to improve my ON condition.
I have horrible tremors of both Legs, Han... - Cure Parkinson's
I have horrible tremors of both Legs, Hands, Head, Hips, RMS of all body parts, and PMLD
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Ramuu
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are you sure you aren’t taking too much? How much do you take and how often?
That could be true due to the phenomenon that with the first dose of mucuna/levodopa, you usually need a bit more due to the accumulated deficit during the night. If you don't reduce the dosage afterwards, an overdose can easily occur during the day, leading to these side effects.
I just take 3 times a day 2 spoons each ( 15 grams ), one at 6.30 AM, it will keep me on till 9.15 AM, second dose at 9.15 AM, it will come up to 11.30 AM to 12.00 Noon. 11.30 AM or by12.00 Noon ,, I will get the tremors, 3rd dose at 12.30 PM, this will work by1.00 pm, I will have my lunch, by 2.40PM, tremor starts, Next dose will be only NEXT DAY MORNING 6.30am, A s MUCANA wporks only in empty stoamch
I just take 3 times a day 2 spoons each ( 15 grams ), one at 6.30 AM, it will keep me on till 9.15 AM, second dose at 9.15 AM, it will come up to 11.30 AM to 12.00 Noon. 11.30 AM or by12.00 Noon ,, I will get the tremors, 3rd dose at 12.30 PM, this will work by1.00 pm, I will have my lunch, by 2.40PM, tremor starts, Next dose will be only NEXT DAY MORNING 6.30am, A s MUCANA wporks only in empty stoamch
I just take 3 times a day 2 spoons each ( 15 grams ), one at 6.30 AM, it will keep me on till 9.15 AM, second dose at 9.15 AM, it will come up to 11.30 AM to 12.00 Noon. 11.30 AM or by12.00 Noon ,, I will get the tremors, 3rd dose at 12.30 PM, this will work by1.00 pm, I will have my lunch, by 2.40PM, tremor starts, Next dose will be only NEXT DAY MORNING 6.30am, A s MUCANA wporks only in empty stoamch
Please ask your neuro for a MAO-B inhibitor. It extends the duration of dopamine in the system.
Please can you suggest me MAO - B inhibitor
Selegiline
I just read the book "Mucana vs. Parkinsons " by neurologist Dr. Rafael Gonzalez He recommends not adding a MAO-b inhibitor with Mucana
If there is any way you could get a Dr. to prescribe carbidopa to go with Mucana it will make it far more effective and will help it to last longer. If you read the book it will help you to learn about the ratio. I believe it's 1 part carbidopa to 4 Mucana
I highly recommend breathing exercises to calm you down.
I have been doing Qi gong exercises and find that helps, you can find plenty of videos on you tube, I like Lee Holden. Try doing 2 xs a day.
Make sure you let go of all past trauma in your body by thinking about it taking a deep breath and saying I'm safe now until you don't have anxiety over it anymore.We can hold trauma in our body.
I know if I'm thinking positive my shaking is minimal. Any type of anxiety or stress makes things worse.
Anything that helps relax you will help.
"1 part carbidopa to 4 Mucana" = Sinemet 25/100 👍😀
you are suggesting me to take Sinemet
No, but not my choice at the moment. The major disadvantage of Mucuna is the dosage because the quality and effectiveness of a natural product can vary. If you are currently taking 15 grams of Mucuna per dosage, it would be approximately equivalent to 500 mg of levodopa. That's a lot. However, you only effectively use a small portion of it. By adding half a tablet of Sinemet 10/100, perhaps half or even less of Mucuna may be sufficient. With much less chance of side effects. I would recommend making changes step by step!
As per per my Ayurvedic Dr., 15 grams of MUCUNA,it equivalent to 110mg of SYNDOPA, which is indian equivalent of Sinemet 10/100
It concerns not only an improved bioavailability of levodopa through the addition of carbidopa, but especially a doubling of the half-life. Due to the higher peak levels, not only can less levodopa be used, but the intake will also be needed less frequently.
The first studies on this matter date back to the 1970s during the introduction of Sinemet.
The Pharmacokinetics and Pharmacodynamics of Levodopa in theTreatment of Parkinson’s Disease (Soo-Peang Khora and Ann Hsu 2007) gives a good overview of this. See in particular Fig. (1).
please suggest me carbidopa , which I can take it with, mucana
You would have to ask your Dr.for a prescription. There is benserazide or carbidopa that would both work. These medicines help carry the mucana to the brain and will make mucana more effective and last longer.If you are unable to get a Dr. to do this I have another suggestion. I read in the same book (Mucana vs . Parkinsons) that beans 🫘 have natural occurring lavadopa and carbidopa and people who eat about 4 oz a day had a reduction in symptoms and there medicines lasted longer. Any type of beans or legumes would work. I hope you get some relief from your symptoms!
Sorry about the spelling 😅 mucuna
Thank you very much. I will try with these options and give you feed back
If you take it with carbidopa it might make symptoms worse, however that may be because it makes the mucuna last longer and build up in your body so it might then start to overdose you. If you feel worse with carbidopa decrease the mucuna .
Alternatively you could try taking half the dose of mucuna but twice as often. We think the shakiness that my husband gets is from the byproducts as it breaks down and from it running out. Taking a half dose between smaller main doses of madopar helped him. He also takes a small amount of clonazapam 0.5 mg cut into quarters and taken throughout the day. If you can’t get that you could try GABA which you can buy without prescription.
GABA you mean GABAPENTINE ?? how much to take ?? how frequently ?? before food or after food ??
No, GABA.
ncbi.nlm.nih.gov/books/NBK5....
“Clinical Significance
GABA is of great clinical significance. Medications that act on the GABA receptor are commonly used as therapeutic medications and substances of abuse, and it is unlikely that any physician, regardless of specialty, will not encounter clinical situations that involve GABA.
There are numerous uses for drugs that modulate GABA signaling. Benzodiazepines are a drug class that exerts its effects by binding to the GABA-A receptor, resulting in increased chloride ion permeability by changing the frequency with which the chloride channels open. They are used in surgical anesthesia, the treatment of epilepsy, REM-sleep disorders, alcohol withdrawal, essential tremor, and muscle spasticity. They are also common drugs of abuse. Ethanol, one of the oldest and most widely-used psychoactive substances, also exerts effects on the GABA-A receptor. Alcohol withdrawal is treated with GABA modulating drugs, such as benzodiazepines. Furthermore, ethanol and benzodiazepines exhibit cross-tolerance with one another due to their similar mechanism of action. Overdosing or taking multiple GABA modulating drugs can result in respiratory depression due to increased GABA signaling in the medulla of the brain stem.”
you meanThe Parkinson's Disease Treatment Book: Partnering with Your Doctor to Get the Most from Your Medications 1st Edition
No, it's "Mucunà versus Parkinson" by Dr.Rafael Gonzalez (neurologist)
I could not locate this book on Amazon or any online platform.
It's on Amazon Maybe it's not coming up because you live in a different area
I believe it is MUCUNA we are speaking of. Not sure why I so often see the spelling here "mucana" and wondering if it's an alternate spelling that I'm not aware of. Also, what about taking green tea extract instead of carbidopa?
Yes, it is spelling wrongly., it is MUCUNA. I am not taking any Green Team, does it help in anyway ??
Green tea delay the conversion of L-dopa to dopamine thereby letting a little more L-dopa get to the brain.
Check section 7.1 to 7.4 here
parkinsonscare.org.uk/green...
mdsabstracts.org/abstract/t...
Green tea info.
1. Green tea is overall good for Parkinson's treatment.
2. Green tea boosts bioavailability of Levodopa.
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