My MDS has recommended switching to Rytary. She says "most" people do better on Rytary. I have been taking one 25/100 immediate release and one 25/100 Continuous release generic C/L at 8, 12, 3:30-4ish and 7:30ish. I also have added citicoline. I get wearing off at about the 3-3.5 hour mark, and I do have pretty severe food interference so as the day goes on it works less well. even if I space it "correctly" from food.
She wants me to start Rytary at three 145's at 8am, 2 and 8pm. She says I can take an immediate release if I wake up earlier in the am. I asked her to also prescribe 95's so that I can adjust more easily and quickly, as needed.
I understand the precaution of not taking sooner than every 5 hours to avoid stacking, and that it's not a good idea to combine regular C/L with Rytary. I decided against entacapone because I already take a few meds that are mildly anticholinergic and I don't want to add to that list.
I'd like to hear from those who have successfully switched to Rytary, what to expect from the transition? Any tips? I know it's different for each person, but it seems people post when they're having problems, not when it's been successful. I'm eight years from diagnosis.
Any suggestions appreciated.