Is PD an autoimmune disease? I was Dx'd with MS then later Dx'd with APS then later developed a DVT, blood clot in my shoulder. I was Dx'd with tumors in my liver. And finally Dx'd with PD. For the first two conditions I was told these are autoimmune, meaning the body is attacking itself. For the third condition, the blood clot, the clotting system is deranged somehow. For the masses in my liver I had surgery to close the arteries feeding the growths. One growth in particular was on the serosal surface, meaning any minor injury such as being kicked by a horse could have led to me bleeding out. Embolizing surgery seemed to clear the problem. But could all of these problems have autoimmune disease as their root?
In medicine they try to find the root problem rather than treating every symptom separately.
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kaypeeoh
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I asked my first Neurologist this question. He said it didn't behave like an auto-immune disease, but he looked at my medical history and said "Never say never". The take out from this for me was, that it could be and auto-immune disease for some, indicating that there is probably more than one cause of PD.
Thanks for the replies. "Never say never" Because of PD I've self-medicated by doing AHT: Autohemotherapy. This is an old treatment using one's own white blood cells to attack abnormal cells in the blood. It doesn't cure MS but can control it. I'm hoping it can do the same thing with PD.
"Researchers at La Jolla Institute for Immunology (LJI) are investigating how the immune system may contribute to Parkinson’s disease, and they hope to help develop better diagnostics and more effective therapies.
LJI Professor Alessandro Sette, Dr. Biol. Sci. and Research Assistant Professor Cecilia Lindestam Arlehamn, Ph.D., have uncovered evidence that Parkinson’s disease is indeed partly an autoimmune disease.
In 2017, the researchers showed that clumps of a protein called alpha-synuclein can act as beacons for certain T cells, causing them to mistakenly attack brain cells and potentially contribute to the progression of Parkinson’s. This was the first direct evidence that autoimmunity could play a role in Parkinson’s disease."
with Parkinson’s disease have memory T cells with a very specific gene signature, and genes associated with targeting alpha-synuclein may very well be causing ongoing inflammation in cases of Parkinson’s.
A link found in the article you linked to:
Scientists uncover new targets for treating Parkinson’s diseaseLJI study suggests therapies could stop T cells from attacking brain cells in Parkinson's
Self-reactive T cells can damage the body’s own cells, including neurons. In fact, self-reactive T cells are the culprits behind many autoimmune diseases
Neurons in many people with Parkinson’s express LRRK2, but the new study is the first to show this gene expressed in T cells.
But many of the genes expressed in these T cells were completely unexpected and not previously linked to Parkinson’s disease. “This finding suggests we found novel targets for potential therapeutics,” says Sette.
This work will confirm whether the same self-reactive T cells found in blood also target neurons in people with Parkinson’s. The team also wants to look for other targets, called antigens, that might be recognized by T cells in individuals with Parkinson’s disease.
Antigen meaning: a toxin or other foreign substance which induces an immune response in the body, especially the production of antibodies.
Interesting indeed. I was diagnosed in May, but am CONVINCED that COVID caused my symptoms, and I just had a barrage of blood test last month which mostly show autoimmune and heart issues. I have had tremor in my leg, and then my hand too. Taking a TON of supplements now, but maybe I just need to do the B1 protocol. Anyone have a link to just the protocol description? Also I need the vegan version of the B1, and that seems to be hard to find. Appreciate all help already given, and to come. 🙏
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