The primary objective of this trial was to assess the impact of minocycline and creatine on the progression of PD and determine if it was futile or non-futile to proceed with further study of these agents. In the study, 200 people with early, untreated PD were equally randomized to receive minocycline, creatine, and a placebo. The study found that both creatine and minocycline should be considered for Phase III trials to determine if they alter the long-term progression of PD.
Where is the Phase 3 trial? Minocycline a... - Cure Parkinson's
Where is the Phase 3 trial? Minocycline and Creatine
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A study record is now available on the Clinical Trials website for the big (N=330) Ambroxol Phase 3 trial (NCT05778617)
Recruitment Status: Not yet recruiting
Estimated Study Start Date: September 2023
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Is anyone supplementing with creatine?
https://www.theenergyblueprint.com/creatine-monohydrate-alex-leaf/?inf_contact_key=b74fb1d342c513f07