Rasagiline (Azilect) and entacapone comparison

[HeartSong]

I'm interested in comparing rasagiline (Azilect) with entacapone. Has anyone had experience with taking both of them but at different times? Can you compare how each affected your PD symptoms? Can you compare the negative side effects of each? Thank you.

[Bailey_Texas]

Do you also take carbidopa-levodopa

[HeartSong in reply to Bailey_Texas]

Yes, I take C/L 25/100 every 2.5 hours.

[Bailey_Texas in reply to HeartSong]

Do you take the entacapone with the C/L?

have taken the two together without a problem. But i can not take entacapone any more because i get severe side effects when i do. I can not take any extender like entacapone or any version including extended release C/L, or Rytary. Just standard release C/L only and i take a lot (18 25/100 3 every 4 hours 24/7) without side effects. I also take 1 6mg Requip for restless leg.

[HeartSong in reply to Bailey_Texas]

Bailey, until now, I haven't taken anything but the C/L. However, tomorrow, I go to see my neuro, and he's probably going to suggest my adding either entacapone or rasagiline to the C/L.

Can you tell me what were the severe side effects you got with entacapone?

[Bailey_Texas in reply to HeartSong]

Night time uncontrolled movements, bad restless leg to the point of no sleep (2 hours at best) loss the ability of speech, random out burst of profanity, mood swings, all at night for hours. almost every night. All went away when i stop taking entacapone. The same thing happenned with rytary and Ext release C/L.

[HeartSong in reply to Bailey_Texas]

Whew! I'm sure I would have had a few random outbursts of profanity myself after dealing with all of that! I'm glad you have found some peace.

[Bailey_Texas in reply to HeartSong]

Thanks

[park_bear in reply to Bailey_Texas]

Just want to add that everyone is different - extentended release / controlled release works much better for me.

Glad you have found what works for you.

[Bailey_Texas in reply to park_bear]

It is strange how these meds work. I need to put a disclaimer everti me i write somthing like that. My doctor wants me to conitiue taking the.mI tried but could not.