Azathoprine caused Liver Cirrhosis!!! - Crohn's and Colit...

Crohn's and Colitis Support

5,543 members1,766 posts

Azathoprine caused Liver Cirrhosis!!!

Bucket13 profile image
3 Replies

Hi Everyone, I’m new here so feeling a little overwhelmed by my recent diagnosis. Here is my story. Diagnosed with Ulcerative Colitis in 2012 which was successfully treated with Azathoprine. However, recently my blood platelets started dropping and I was given a liver ultrasound where I was told it felt stiff with scarring but then following a liver biopsy my results were ‘liver cirrhosis’ !! I’m now awaiting to speak to a liver specialist in Birmingham and hope they can find medication to treat my UC but without causing further harm to my liver. Has anyone else experienced liver cirrhosis caused by azaphoprine? Xx

Written by
Bucket13 profile image
Bucket13
To view profiles and participate in discussions please or .
Read more about...
3 Replies

How long were you taking the Azathioprine? I was on it for 2 years to treat my Vasculitis and don't seem to have a problem.

Bucket13 profile image
Bucket13 in reply to

hi,, I was on azaphoprine for almost 10 years, I had 3 monthly blood tests yet they never got highlighted!!!! What’s the bloody point and I presumed all ok as I feel fine and they managed my UC. Now I’m waiting to be prescribed something else, which will help my UC but not affect my liver. Im on steroids at the no (only have 5 left and my consultant on holiday again). They don’t seem to care and his secretary makes me feel like I’m annoying

Hopefully you will be fine and only on it for a short time.

012703060610 profile image
012703060610

While I was on Azathioprine at one point, it didn't work well with my gut. I ended up at the max dose of Methotrexate of 25 mgs injection (other autoimmune issues as well as GI). My bloodwork was trending up on my liver enzymes so we reduced my dose back to 20 mgs. I highly suggest you ask your Dr to look into LDN (Low-dose naltrexone). I just started this about a month ago and it has pushed most of my autoimmune symptoms back and without the methotrexate. I encourage all on this site to research this. I have it made at a custom pharmacy. Sharing random link for you to read. Could be a good solution!

americanintegrative.com/low...

Not what you're looking for?

You may also like...

Crohn's associations with DLE and pancreatic,liver cirrhosis

hello, are there any of you like me, it's been months since I had to go to the hospital because of...
Christy_cd profile image

Leaky liver

Hi guys, I’m not really sure where I need to be I’ve had all the scans mri tubes put everywhere...
Manxie831 profile image

Raised Liver Markers - Octasa/ Mesalamine?

I started taking Octasa for Crohns in October 23. Just had blood tests (for another issue) and dr...
VV_1990 profile image

Has anyone had liver problems whilst on Mercaptopurine?

Hi everyone, In as brief as I can I was diagnosed with UC in May this year with a severe flare, no...

Help please for daughter abroad

I am posting on behalf of my daughter who lives and works in N Cyprus . I hope that is alright. She...
bones-bones profile image

Moderation team

willow24 profile image
willow24Administrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.