Cardiac Preconditioning and BCL-2: Cardiac... - CLL Support

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Cardiac Preconditioning and BCL-2

Lavinia-Blue profile image
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Cardiac Preconditioning: How to Use Mini Heart Attacks to protect against Heart Attacks

youtu.be/de4s4AjlsqU?featur...

At around 3:40 into the video is an ​interesting​ finding, if I understand this right. Wonder how BCL-​2 therapies​, such as Venetoclax​, affect this phenomenon? ​

Anyone care to take a crack at this?

​"Venetoclax attaches to a protein called Bcl-2.[8] This protein is present in high amounts in CLL cancer cells, where it helps the cells survive for longer in the body and makes them resistant to cancer medicines.[8] By attaching to Bcl-2 and blocking its actions, venetoclax causes the death of cancer cells and thereby slows down progression of the disease.​" en.wikipedia.org/wiki/Venet...

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Lavinia-Blue
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AussieNeil profile image
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Lavinia, that video is click bait to encourage paid subscriptions. If the phenomenon is correct in humans, venetoclax would negate it.

Neil

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