I have seen other discussions re bad mutations , on my regular letter to my doctor from my haematologist it states :
Chronic Lymphocytic Leukemia associated with high risk variants including loss of the LEU and ATM genes.
As per my normal blood results, do these have a high and low level and if so what are they, thanks for any info you may have
Will
Hi Will,
It would be best if you could obtain a copy of your test results, as these will state what was found. Pathology labs unfortunately don't necessarily have a standard way of reporting.
Neil
Hi Neil, the ATM was mutated at 37 out of 100 and the DLEU 1&2 was 65 out of 100
You can correct your posts via the 'More v'.. Edit option under your post, but I've made that easy to make typo for you.
DLEU1 and 2 are associated with the most common deletion in CLL, 13q14, which is the most favourable deletion. pubmed.ncbi.nlm.nih.gov/327...
Keep in mind that these results can change over time should sub-clones become dominant, but as cajunjeff noted earlier, "The prognosis for 11q cll has improved greatly with the advent of btk drugs like ibrutinib".
Neil
Mutation of the ATM gene is associated with 11q cll. The prognosis for 11q cll has improved greatly with the advent of btk drugs like ibrutinib. Here is an article that might help someone understand the relation between the ATM gene and 11q cll:
Leu1 and Leu2 are 13q. This would be good if it was the only mutation.
IVGH mutation status
IGVH Mutation Status
13Q Deletion and ATM Mutation 
IGa levels
Cll and my mutation
