does it matter which RSV shot I get?

[IaBoy62]

My hematologist/oncologist (affiliated with MDAnderson) said I should get RSV shot, but he mentioned he needed to know which one I would be receiving but offered no more details or reasoning.

I can get Arexvy or Abrysvo on October 1.....so has anyone heard anything why one would be preferred over the other?

My WBC is fine but my IG levels have been low since last year when I had covid.

I left a message for his nurse but have not heard anything and I am not calling again and will just choose one the pharmacy recommends.

Thoughts?

Thanks in advance!!

[lankisterguy Volunteer]

Hi laBoy62,

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We have seen several suggestions from YLE (Your Local Epidemiologist) - here:

healthunlocked.com/cllsuppo...

RSV vaccine for older adults

What: For the first time, an RSV vaccine is available and from two manufacturers— GSK and Pfizer. Both effectively protect against severe illness, with 82-86% efficacy. The two vaccines are slightly different in design, but only at a microscopic level. And side effects like fever and body aches are uncommon.

Who: People ages 60 and older “may” get the vaccine in the U.S. In the U.K., those over 75 years “should” get the vaccine. People with underlying health conditions (like heart or lung disease or diabetes) and those living in long-term care facilities should strongly consider the vaccine.

When: They are available now. RSV vaccines do not wane as quickly as flu and COVID-19 vaccines, so getting one now should protect you throughout the entire season (and maybe even next season).

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Len

[IaBoy62 in reply to lankisterguy]

Thank you for the link….I love charts and graphs!

[Sillysand in reply to lankisterguy]

To Lankistergug

"Both effectively protect against severe illness " ???

What data, research and or study are you basing this on ? And does it apply to us CLL people ? ? I would like to read the specifics on HOW this wii protect me as a person with CLL.

Respectively

Seeker

[lankisterguy Volunteer in reply to Sillysand]

Hi Seeker909260,

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You are confusing me with the writer:

facebook.com/profile.php?id...

yourlocalepidemiologist.sub...

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Len

[Sillysand in reply to lankisterguy]

i was replying to your reply " we has several suggestions "

[Newdawn Administrator in reply to Sillysand]

Seeker, your reply to Len is somewhat curt and appears to misunderstand that he’s directly quoting from the authors in the link he provided. He is therefore not responsible for the scientific veracity of the comments made even if it appears to be from a reliable source. Len isn’t basing this on any personal data, research or study but simply presenting the information for the reader to discern and take advice on.

As the previous link Len provided from YLE says;

‘We know many people have many questions. Please comment or send them to us, as we plan on following up with a FAQ. And, of course, it’s always a good idea to consult with your pharmacy or clinician.’.

I think this should be the advice to follow although being from the U.K., this doesn’t yet have direct relevance to Brits.

Newdawn

[SofiaDeo]

I am thinking they just want it as a data point, to see if any patterns emerge between the groups of patients. Then if they ever need to, they can quickly sort out who got what.

[jonathan7176]

I wish we could get it in the UK. Nothing on whether it will be made available to older immunosuppressed through NHS.

[CLLerinOz Administrator]

I don’t recall seeing any research specific to CLL that would indicate a preference for one RSV vaccine over another.

One difference between the two vaccines, however, is that one, RSVPreF3 (Arexvy) by GSK, contains an adjuvant and the other, RSVpreF (Abrysvo) by Pfizer, doesn’t. Other than that, both vaccines are recombinant protein vaccines.

cdc.gov/vaccines/vpd/rsv/hc...

healthunlocked.com/cllsuppo...

CLLerinOz

[lexie]

Thanks for asking this question. Was wondering the same. When Covid vaccines were initially released my CLL specialist urged me to get the first one available. I didn't have to choose which made it easier. 🤔