Loxo305 trial

[Alex830]

Is anyone currently enrolled in this trial? My doctor mentioned this as maybe an option besides V&O. I looked at it but apparently there are several phases, this is the one we are looking at:

BRUIN CLL-322: a Phase 3 open-label, randomized study of fixed duration pirtobrutinib (LOXO-305) plus venetoclax and rituximab versus venetoclax and rituximab in previously treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Any feedback is appreciated.

[AussieNeil Administrator]

Members Osprey69, steve5441 and UKfulloflife joined a LOXO-305 trial.

Neil

[Osprey69]

I am currently in Loxo trial- as single agent. Started trial in 6/19 with very few side effects. I am now starting to show alittle resistance but will continue with trial until my numbers indicate I have to make a change. Bruin CLL trial with that combination looks good. Best of luck with your decision. Fran