Huge drop in PLT(platelets) while under CLL treatment with RITUXAN

[larrcow]

Did anyone experience a huge drop in PLT(platelets) while under CLL treatment with Rituxan? Mine has gone from 389 to 76 after the 4th and last treatment. Doctor wants to wait to see if PLT will improve.

Thanks,

larrcow

[lankisterguy Volunteer]

Hi larrcow,

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Platelet issues are common, especially just before starting treatment and during treatment with most of our drugs.

For some it is a short duration and as the bone marrow recovers from treatment the numbers improve on their own.

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If not, then the doctors need to step through "differential diagnosis" to eliminate the common causes one by one, to zero in on the root cause.

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You can see some discussion in other postings by looking for the box on this page labeled: "Related Posts

*2nd Treatment - Acalabrutinib vs. Venetoclax + rituxan healthunlocked.com/cllsuppo...

*RITUXAN transfusion for CLL patient with ITP (Low platelets)? healthunlocked.com/cllsuppo...

*platelet levels still dropping healthunlocked.com/cllsuppo...

*Untreated CLL, on steroids for AIHA - awaiting cause of a drop in platelets healthunlocked.com/cllsuppo...

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And here is a link to the 1,548 times platelets were mentioned in previous postings

healthunlocked.com/cllsuppo...

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Len

[larrcow in reply to lankisterguy]

Thanks for the info and links. Just another wait and see.

[thb4747]

Hi Larrcow,My platelets were 171 when I was diagnosed in September 2001. I’ve had many treatments — 18 of which involved Rituximab. Suffice it to say that 198 is the highest I’ve ever recorded in 21 years, 76 is the lowest. Sadly, I think it’s part of your new normal. I’m still here 21 years later. I wish you well.

[morepork in reply to thb4747]

I'm glad you're still here too Rob. My platelets yoyo between 76 - 80 , since starting

Ibrutinib around 6 years ago. 😊

[thb4747 in reply to morepork]

Glad you’re still here too!

[larrcow in reply to thb4747]

Sounds good. Thanks

[larrcow in reply to thb4747]

Thanks you for the feed back. I guess this is another wait and see.