Covid anti-body study

[Dawson21]

I was contacted by Imperial College to participate in the Melody trial to determine what levels of anti-body might exist following various medication regimes and courses of vaccination. Did my test today and just for general information - it was totally negative = no anti-bodies at all. I'm signed up now for my 5th vaccine and will see what happens (last booster almost 6 months ago). I do wear a mask in crowded situations and shops, otherwise no specific precautions taken.

[annmcgowan]

Hi I tested negative after 4th vaccine and have not been tested since. I have had my 5th vaccine. I am on ibrutinib and research is showing this is common for those taking ibrutinib.Ann

[Dawson21 in reply to annmcgowan]

I'm on Venetoclax and due a 5th shot this month - I am not surprised to be negative but had been hopeful!

[annmcgowan in reply to Dawson21]

Me too.Ann

[RobertCLL]

How did you get onto the trial? I looked at their website and the trial was not yet open for blood cancers.

[Dawson21]

I received an invitation through the post - not sure why - presumed it was because I was registered as "Highly vulnerable". They asked all the questions about CLL treatment, when started, what stage I was at, etc. So sounded like they intended to recruit me.

[Kingfish6]

I'm in the same boat. Little antibodies after Spike; no protection with Chain test. Got immunoglobulins tested- low. Asked doc about 5th VAX. He said won't do anything, so finally got Evusheld. I think this might be the way to go every 6 months, plus every VAX laid me up for 2 days.

FDA just acknowledged best to get Evusheld every 6 months but what does it mean for the Vax for us immunocompromised. At the same time, Evusheld supply is limited as Feds bought only 1.7m doses, & has no $ for COVID at this time.

[Dawson21]

An update. Finally tested positive for Covid on Dec 20th and started Paxlovid on the 22nd. Today, the 29th tested negative. Overall very mild effects, hardly a cold. So either the vaccinations did gave some lasting effect or Paxlovid saved the day. Out into the wide world again today.