Ibrutinib. Capsules are being discontinued and replaced by tablets.

[RogerPinner]

Subsequent to my query a few days ago asking whether (in the UK) ibrutinib would in future only be available in tablet form, the answer from Jannsen is YES. They were understandably reluctant to discuss their reasons with me but confirmed that the tablet should be taken whole, not be crushed or cut up.

No doubt I will learn to cope, but for those who have difficulty swallowing, this may be a problem.

Thanks everyone who has shown interest in my original question.

Roger

[mrsjsmith]

Thanks Roger,

Something else to worry about now. ! I have trouble swallowing large pills. Will it be 1x420 or 3x140 did they say ? I live in hope of a reduced dose one day 🤔

Colette

[Hidden in reply to mrsjsmith]

in usa they make 4 different strength tablets.

[mrsjsmith in reply to Hidden]

Thank you,

In the U.K. they seem to come from Belgium, so we shall see what we end up with.

Colette

[Hidden in reply to mrsjsmith]

i should clarify, we have 4 sets of tablets sold in usa. However the packages say active ingredient made in china. I don't actually know where they are pill formed and put in packages. they say distributed by pharmacyclics.

[mrsjsmith in reply to Hidden]

All mine says is manufacturer Janssen.

Colette

[Hidden in reply to mrsjsmith]

does it say manufactured or distributed by

[mrsjsmith in reply to Hidden]

It says Marketing Authorisation Holder Janssen-Cilag and Manufacturer Janssen Pharmaceutica both in Belgium.

[Workers in reply to mrsjsmith]

Hi

I was told by my consultant it will be one 420 tablet, because he said make sure you don’t take 3 !!

[mrsjsmith in reply to Workers]

Oh dear ! I hate change. Yes taking three without thinking will be a big worry ! Big red stickers everywhere 🤔

Colette

[mrsjsmith]

Thank you Scott,

Soon after my tonsillectomy I came close to choking on a painkiller and then had a panic attack, and since then I have been very careful.

Colette x

[josephinef]

Hi RogerPinner,

I haven’t heard anything as yet regarding ibrutinib is going to be in tablet form. All I can say is yuk. I have difficulty in swallowing tablets also. When I had a stint in hospital nearly 2 years ago a visitor noticed that I was having difficulty swallowing the tablets and she told me to put them under my tongue and then drink. It works for me.

Good luck with your health.

Take care.

Kind regards Josephine from Australia 🇦🇺