I have posted before but now have all of my tests done. I wanted to see if the members here who know more than I do agree with my doctors recommendation of watch and wait? My age 47, good health,slight fatigue, platelets good. WBC slightly off. Alkaline Phosphate 216 normal is under 140.( not sure the cause of this but rising pretty quickly) Slight Anemia but barely under normal. Lymph nodes in stomach slightly enlarged. Lymph nodes in neck can’t be seen but slightly enlarged. Biopsy showed CLL in 5 of 6 removed nodes. CD 38 positive and unmutated. FISH just said within normal range for other markers. I think my Doctor is correct in watch and wait but wanted to see if anyone here thinks I should get a second opinion? I am studying and learning everyday but know their are many people with a lot more knowledge than me.