A good-ish story: I have unmutated CLL, diagnosed 10 years ago when I was 52. I upturned my life about five years in, turned to macrobiotics, meditation, less stress. Recently I left a bad marriage. I haven't needed treatment all these years. So the WW can last a long time even with unmutated. Alas, now my WBC is up, my spleen is 13 cm and I'm showing signs of slight anemia. Doc says it's time to treat. I've got six weeks before labs come back to tell him which drugs are better. Until then, I'm pulling out all the stops like I read some of you have. Drawing blood today to get a baseline and will see if I can make changes. Agree with somebody here, better not to wait til you need treatment to try alt options. Super tricky physically and head-state wise to say not to the drugs. What a ride.