I need some help! I have been on imbrivica for 8 months. I decided it was time to start running again and I went for a short run 1 1/2 mile. The next day i had so much pain in both knees. A week later I can't even walk. The pain is so bad. The doctor is holding my imbrivica and had me on prednisone for a few days but no improvement. Has this happened to anyone? I do not have gout. I will see doctor next week.