A global snapshot of leukemia incidence

[AussieNeil]

FROM THE LANCET HAEMATOLOGY:

"Chronic lymphocytic leukemia incidence was highest for men in Canada (4.5 per 100,000), Ireland and Lithuania (4.4), and Slovakia (4.3). The incidence was highest for women in Lithuania (2.5), Canada (2.3), and Slovakia and Denmark (2.1). Incidence in the United States was 3.5 for men and 1.8 for women. At the other end of the scale, the lowest rates for both men and women were in Japan and Malaysia (0.1), the investigators’ analysis showed."

Full article: mdedge.com/hematologynews/a...

Neil

Photo: Riceflower. Perhaps given the lower incidence in Asia of CLL we should eat more rice, drink more green tea or is is just genetics?

[SeymourB]

Neil -

This is really interesting!

I have to wonder how standards for diagnosis change across the world, plus how cultural factors that may prevent patients from seeing a doctor in the first place. Access to inexpensive, regular blood testing would seem to be a part of the difference between countries. Cultural factors may skew differences between men and women. Nevertheless, I have no doubt that some of the differences are real.

I also notice that some of the data are estimates from 2012, while other data are from national cancer registries between 2003-2007. The abstract is not clear which periods are used for the CLL numbers.

=seymour=

[Eric_68]

I have read it Genetics

[Hoffy]

I grew up in Wisconsin. I swim in lakes near cornfields and he’s to smell the herbicides used on the cornfields I wonder if that could account for more of a northern bias .

My father got auto immune hemolytic anemia after a summer swimming in our lake near our house. And I know someone else who got acute my Lloyd leukemia at the end of two summers . She had treatment it went away and then came back after the next summer .

Genetics are a factor is well. The other question is vitamin D .

Hard to tell exactly

Hoffy

[fell]

Yikes, Canada! 😕

[Cllcanada Top Poster CURE Hero]

Doesn't suprise me, considering 3/4 of Canada is on the Canadian Shield with high Radon counts, recently a new risk for CLL.

ncbi.nlm.nih.gov/pubmed/265...

ncbi.nlm.nih.gov/pubmed/288...

[Fant1924]

Wonder what the rate is for Vietnam Veterans?

Dennis, 71, Ibrutinib

[Cllcanada Top Poster CURE Hero in reply to Fant1924]

Don't know overall, I would expect the incident to be higher than the general population due to Agent Orange..

ncbi.nlm.nih.gov/pmc/articl...