Hi..my mum has cll since 2001 and she has had 4 major infections from Sept on..she was on imbruvica but became too ill to continue. They just can't seem to find source of these infections...she gets horrible fevers every 4 hrs..freezing cold shaking then hot ..sweating etc. Doctors say its nothing to do with her cll and indeed her bloods have shown nothing major except elevated white cells i.e infection. She gets weaker with every infection. Anyone out there relate?Heart breaking.