"New technologies such as the CRISPR-Cas9 offer the possibility of altering an individual's genome, or even a generation's genome.
Most of the research involved ex vivo experiments -- removing cells, editing them in a lab and then replacing them.
While this process is "relatively easy" for immune cells or blood stem cells, "this isn't possible with most bodily tissues," noted the New Scientist's Michael LePage.
Regarding other conditions studied through ex vivo experiments, Porteus said his lab developed a method for correcting mutations of sickle cells in patients' stem cells. If a cure is found, it might take only a few "tweaks" to then find a cure for other illnesses, such as severe combined immunodeficiency, he noted."
Full article in Medpage Today: medpagetoday.com/genetics/g...