Friends,
To understand why BCL-2 is such an attractive target in CLL and with the promise of venetoclax (ABT-199) hopefully coming soon, here is the very easy to digest nine minute lecture given by Dr. Michael Choi out of UCSD: cllsociety.org/2015/11/targ...
The introductory explanation on our website summarizes the background on Venetoclax’s downside, tumor lysis syndrome and includes links to two trials.
Stay strong.
We are all in this together.
Brian