I know it is not the largest concern of those of us with CLL, but here it is. In the 6 months I have been on Ibrutinib I have felt better than I have in the last 10 years. My nails, however, seem to have stopped growing and break constantly and rip and tear. My hair is also falling out, although it has slowed considerably. My skin, particularly hands and feed and dry, cracked, and very sore. Had my thyroid checked and all is well. It is a small price to pay for the Ibrutinib, just wondering if anyone else has had a similar experience.