Those with CLL have a significantly higher risk of developing skin cancers and we've just had a reminder of the importance of remaining vigilant for these:
New research published today in the American journal Cancer Epidemiology, Biomarkers & Prevention shows that people who get non-melanoma skin cancers – particularly before the age of 25 are also at increased risk of developing other cancers - the associated risk works the other way around too:
Some excerpts from an article by Rodney Sinclair in 'The Conversation', a practicing dermatologist who sees patients with skin cancer on referral from general practitioners. He is the dermatologist spokesperson for Cancer Council Victoria's (Australia) skin cancer campaign and is a member of the scientific research committee for the Australasian College of Dermatologists.
"We’ve known for some time that sunlight suppresses the skin immunity – that’s why some people get a cold sore during a holiday in the sun. This is because UV exposure suppresses the immune system in a number of specific ways: one is to allow herpes virus reactivation (a cold sore).
Another is to suppress tumour surveillance by the immune system. This is the natural protective mechanism the body uses to fight developing skin cancers."
and by analysing data from the All England Record-linked Hospital and Mortality data set collected between 1999 and 2011...
"We found that for those who had Non-melanoma skin cancers (NMSC), the relative risk for developing cancers of the bladder, brain, breast, colon, liver, lung, pancreas, prostate, and stomach remained consistently elevated when compared to the control group for the entire period of the study, and the risk for cancers of the brain, colon, and prostate increased with time.
We also identified that those who had NMSC before the age of 25 were 53 times more likely to get bone cancer, 26 times more likely to get blood cancers, 20 times more likely to get brain cancer, and 14 times more likely to get any cancer excluding those of the skin."