I am the wife of a 52 year old patient with PSC. He was transplanted at the end of November and has experienced rejection ever since with steroids and other treatments not working. It appears it is because his antibodies are so high. The consultants are now thinking about retransplantation, because the liver biliary tree is failing, in the hope that the new liver will not be rejected in the same way. In the meantime, he seems quite well at the moment but for how long this will last I don't know.
PSC is a condition that apparently, once showing with blood tests etc, can suddenly make your health go downhill very quickly so transplantation was recommended even with very few symptoms - we were told that it can be too late for some people if they leave the transplant until later - hence the decision to go ahead in November.
This is so hard as prior to his operation back in November, you wouldn't have known he was so poorly (no symptoms, only slightly tired), so he's gone from a very fit man (mountain biking etc) to someone on their knees with a failing transplant. Has anybody else experienced rejection in this way and needed a second transplant? What are your experiences? I have to stay positive but admit to myself, this is going to be very difficult.