I have been taking Bumetanide (1 mg daily) and Spironolactone which is a potassium conserving diuretic (200 mg daily) for cica 2 years and this is to control ascites that has resulted from my AIH and Cirrhosis. It works reasonably well although ascitic fluid still continues to accumulate in the abdomen but at a much slower rate than it did before going on to the medication.
Unfortunately one of the main side effects of Spironolactone is
that it is a common cause of Gynecomasia and I too am suffering from that side effect. It is on occasions painful but so far I have been able to endure and cope with it. However one aspect I am not too happy about is a cosmetic one and that is the development of male boobs / moobs or whatever it is people tend to call them.
From researching the literature etc it appears that Amiloride which is another potassium conserving diuretic is sometime used in place of Spironolactone when Gynecomasia has occurred but it is said it is not as strong and also has a shorter period of effectiveness after ingestion. I have no previous experience of taking Amiloride but nevertheless am thinking of asking my liver specialist who I am due to see again in about two weeks time if it can be prescibed for me instead of Spironolactone.
Before speaking to the Specialist it would be useful to know whether anyone else on this forum has experienced changing from Spironolactone to Amiloride and if so how effective was it in continuing to control the ascites. Additionally whether as a result of the change there was a resolution of the Gynecomasia?
If anyone has had this situation and is prepared to share their experience I shall be pleased to read and learn from it.