I hope you are enjoying the holidays! I have been posting questions as my tests have changed, because I can't seem to get any solid answers from my doctors. I apologize in advance if you have read one of my crazy emails, but I am so scared and just can't seem to get any solid answers.
Long story...attempting to make it short. I was admitted to the hospital after falling down the stairs and hitting my head on February 8th of this year (2014). Had a concussion/traumatic brain injury that we have dealt with and are still dealing with. All of my blood tests came back normal, with the exception of my AST and ALT. I'm just going to write this down chronologically, because I think you'll be able to follow this easier. Prior to this, I have never had any enzymes that were high.
January 24th Was put on a drug called perphenazine for anxiety
February 8th AST 58 ALT 72
February 27th AST 63 ALT 108
March 5th Immediately stopped taking the perphenazine after doc tells me it can be toxic to liver
March 5th Liver Ultrasound Moderate to severe fatty infiltration of liver, all other findings unremarkable
March 5th Doctor told me I had NASH, based on high liver enzymes and fat found upon ultrasound
March 6th Freaked out for most of the day.... :o) (Generalized Anxiety Disorder will do that to ya!)
March 7th Got off my fat fanny (was weighing 190 at 5 feet 5 inches) and started exercising/eating right
April 21st AST 37 ALT 59 (According to my lab, AST now normal, ALT 3 points over limit)
July 21st AST 33 ALT 33 (Now both within range according to lab my doc uses)
November 6th AST 21 ALT 24
November 6th Have lost 60 pounds and now weigh 130lbs. BMI 21.6. YAY!!!
Will probably have another liver scan in March. Still eating healthy and walking an hour in the morning and one at night. Did take a 6 week hiatus from walking a couple of months ago because the weather was so yucky. Now I have a treadmill, so I won't be able to use that excuse anymore! :o)
So, given all of this information, my doctor (PCP) and my gastroenterologist are both saying that I might have never had NASH in the first place but that they aren't sure. They've said my enzymes could have been up due to liver toxicity resulting from the perphenzine and came down due to stopping the medication. They've also said that it could be that my enzymes have come down from my diet and exercise (or as I like to call it....my lifestyle change).
So, at this point, NOBODY will do a biopsy....not that I want one, but I have one small, minor question. DO I HAVE NASH OR NOT????????? I feel good, have a great appetite, confess that I take a nap during the day as my new anxiety medication makes me sleepy. I don't have diabetes, in fact, glucose levels had gotten to about 110 which was heading in that direction when I was at my heaviest. My glucose was last checked in July and was 101 and continuing to come down. One of the side effects of the medication I stopped taking was high glucose levels. I have low to normal blood pressure and take pravastatin due to high cholesterol. It is now well under limits. High cholesterol runs in my family.
I am so confused. I thank you all for putting up with a nut like me. I am a 43 year old married female with two feisty teenage girls. I want to see them go to college, graduate from college, get married, have their own children and MOST IMPORTANTLY, watch them suffer as their teenagers drive them completely bananas!!! (I know that my mom is really enjoying watching me right now with my sassy girls, as I was a TERRIBLE teen)!!
Any ideas? Is there a way to know if your NASH has been reversed besides biopsy? Because obviously they won't do one. In the same token, is there any way to know if it is still progressing? I have read so many scary stories of people being fine one day, and then being in the ER the next, finding out that they have NASH related cirrhosis. I don't want to be that person.
Thank you all for your patience with a crazy girl filled with anxiety. I really do appreciate it and thank God that this board is here. God bless you all!
Robin the Anxious Nut