Just trying to get an idea what may be next for me. I have sort of AIH/PBC overlap, well autoimmune cholangiopathy to be precise, diagnosed a while ago, now found to have progressed to fibrosis. Began on steroids earlier this year, now down to 15mgs Pred daily, and LFTs are better though still slightly raised, but stable.
Started on Azathioprine a couple of months ago, had dreadful adverse reaction, last week tried again with Mercaptopurine (specialist did warn me I had 50/50 chance of similar, as chemically both drugs are very similar). Lo and behold, after one dose, I had similar reaction. So not only do I have a disease nobody's heard of, I can't take the two best researched drugs for my disease.
Anyone been in similar position, and if so what are you on? Has anyone had Mycophenolate, for example? esp after having bad reaction to first two?