My wife recently diagnosed triple positive breast cancer, Ki-67 - 60%. Pathologic stage : pT2N1a , no family history of cancer. Tumour size; 2x 1.7x 1.1 cm. (not sure what else I should print from the Histopathology report)
Age 36 years. She was breast feeding our 1 year old (second) kid when we found it out.
Received first TCH Chemo ( Docetaxel + Carboplatin + Herceptin).
My question is :
Doctor has asked Germ Line Mutation Analysis, what it is going to found ? how it can effect treatment? Do we have enough data to to drive suggestion/treatment with enough confidence?
[ I have basic understanding of Germ Line Mutation Analysis. if I understand correctly only less then 10% cases are due to inheritance. Also Her-2/neu is not carried in inheritance. ]