Tamoxifen/herceptin with radiotherapy - Breast Cancer India

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Tamoxifen/herceptin with radiotherapy

anshul_15 profile image
3 Replies

Can tamoxifen (daily 20mg) and Herceptin (every 21 days- 440mg) be both given during radiation therapy ?

Can all three be given together or tamoxifen / herceptin be stopped during radiotherapy ?

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anshul_15 profile image
anshul_15
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bhavika23 profile image
bhavika23

I m sure of herceptin . It can be given during radiation. BT tamoxifen nt sure. Usually all meds stop during radiation ñ start aftr 3 weeks of finishing. Still make sure with ur doc. Herceptin for sure can be given

sumeet_shah profile image
sumeet_shahAdministrator

SOme radiation oncologists prefer to hold on Tamoxifen till radiation is complete. While some give during radiation. Both are fine. But I would prefer to hold on Tamoxifen and start after radiation.

roxboxfox profile image
roxboxfoxRadiationOncologist in reply to sumeet_shah

Tamoxifen should ideally not be used concurrently with Radiation especially if there is 3 field Radiation due to some statistically significant increase iñ chances of Lung fibrosis as seen in few very early trials of 80s and 90s.

There is no benefit starting Tamoxifen along with Radiotherapy for sure...

Herceptin can be used during Radiotherapy.. No issues till date.

Rohit

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